説明
Interleukin-4 (IL-4) is a cytokine that belongs to the interleukin family. Interleukin 4 is mainly produced by T cells, B cells, macrophages and other immune cells.IL4 is a key regulatory molecule that plays an important role in the Th2 type of immune response. Interleukin 4 has a variety of biological functions that promote B cell class switching to IgE and IgG1, thereby enhancing the effects of humoral immunity. In addition, IL4 inhibits the activation of macrophages and dendritic cells and suppresses their release of inflammatory cytokines. In clinical practice, interleukin 4 is widely used in the treatment of allergic diseases, such as asthma and allergic rhinitis.
This product is available as Fluids, high activity, high purity, low endotoxin, NO labeling.
Product Properties
|
Synonyms |
Mouse B cell growth factor 1; BCDF; B-cell stimulatory factor 1; BCGF1; BCGF-1; binetrakin; BSF1; BSF-1; IL4; IL-4; IL-4B_cell stimulatory factor 1; IL4E12; interleukin 4; interleukin-4; |
|
Species |
Mouse |
|
Source |
HEK293 Ceslls |
|
Sequence |
His21-Ser140 |
|
Accession |
P07750 |
|
Tag |
NO |
|
Predicted molecularmass |
13.6 KDa |
|
Endotoxin |
<0.010 EU per 1 μg of the protein by the LAL method |
|
Purity |
> 95%, determined by SDS-PAGE |
|
Activity |
Measured in a cell proliferation assay using HT2 mouse T cells. The ED50 for this effect is 0.3-1.5 ng/mL |
|
Formulation |
Dissolved in sterile PBS buffer. |
|
Appearance |
Fluids |
Shipping and Storage
-85~-65℃ storage, valid for 1 year after receipt.
Avoid repeated freezing and thawing, centrifuge before opening the vial. It is recommended to aliquot for one experimental use, after aliquoting, freeze at -80℃.
Cautions
1. For your safety and health, please wear lab coat and disposable gloves.
2. This product is for scientific research purposes only.
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