説明
Interleukin 19 (IL-19) is a glycosylated protein secretion that exists as a monomer.IL-19 is mainly produced by monocytes and its expression is induced by LPS, IL-4, and GM-CSF.IL-19 is expressed at a low level in B-cells.IL-19, IL-20, and IL-24 are members of the IL-20 subfamily of the IL-10 family, and they can all bind IL-20 receptors and cause activation of the STAT3 signaling pathway.IL20R2 can be paired with IL20R1 or IL22R1 to form either a type I IL20R complex or a type II IL20R complex.IL-20 and IL-24 both have signaling pathways, whereas IL-19 can only signal through the IL-20 receptor complex.
This product is available as Liquid, high purity, high activity, low endotoxin, No labeling.
Product Properties
|
Synonyms |
IL-10C; IL19; IL-19; interleukin 19; MDA1; melanoma differentiation associated protein-like protein; |
|
Species |
Mouse |
|
Source |
HEK293 Ceslls |
|
Sequence |
Leu25-Ala176 |
|
Accession |
Q8CJ70 |
|
Tag |
No |
|
Predicted molecularmass |
17.6 kDa |
|
Endotoxin |
<0.010 EU per 1 μg of the protein by the LAL method |
|
Purity |
> 95%, determined by SDS-PAGE |
|
Activity |
Measured in a cell proliferation assay using BaF3 mouse pro-B cells transfected with human IL-20 R alpha and human IL-20 R beta. The EC50 for this effect is 4-20 pg/mL. |
|
Formulation |
Dissolved in sterile PBS buffer. |
|
Appearance |
Liquid |
Shipping and Storage
-85~-65℃ storage, valid for 1 year after receipt.
Avoid repeated freezing and thawing, centrifuge before opening the vial. It is recommended to aliquot for one experimental use, after aliquoting, freeze at -80℃.
Cautions
1. For your safety and health, please wear lab coat and disposable gloves.
2. This product is for scientific research purposes only.
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