Beschrijving
Interleukin-5 (IL-5) is a hematopoietic growth factor that stimulates the proliferation and activation of eosinophils.IL-5 is produced by mast cells, T-cells, and eosinophils, and plays an important role in inducing cell-mediated immunity against parasitic infections and certain tumors.Elevated levels of IL-5 can lead to eosinophilia, which may cause asthma and other allergic diseases. Human and mouse IL-5 are cross-species reactive.
Recombinant human IL-5 is a 26.2 kDa disulfide-linked homodimeric protein containing two 113 amino acid chains. This product is supplied as Fluids, high activity, high purity, low endotoxin, NO labeling.
Product Properties
|
Synonyms |
IL5; IL-5; IL-5T-cell replacing factor; interleukin 5 (colony-stimulating factor, eosinophil); interleukin-5; |
|
Species |
Mouse |
|
Source |
HEK293 Ceslls |
|
Sequence |
Met21-Gly133 |
|
Accession |
P04401 |
|
Tag |
NO |
|
Predicted molecularmass |
13.1 KDa |
|
Endotoxin |
<0.010 EU per 1 μg of the protein by the LAL method |
|
Purity |
> 95%, determined by SDS-PAGE |
|
Activity |
Measured in a cell proliferation assay using TF1 human erythroleukemic cells. The EC50 for this effect is 0.04-0.15 ng/mL. |
|
Formulation |
Dissolved in sterile PBS buffer. |
|
Appearance |
Fluids |
Shipping and Storage
-85~-65℃ storage, valid for 1 year after receipt.
Avoid repeated freezing and thawing, centrifuge before opening the vial. It is recommended to aliquot for one experimental use, after aliquoting, freeze at -80℃.
Cautions
1. For your safety and health, please wear lab coat and disposable gloves.
2. This product is for scientific research purposes only.
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FAQ
Het product is alleen bedoeld voor onderzoeksdoeleinden en is niet bedoeld voor therapeutisch of diagnostisch gebruik bij mensen of dieren. Producten en inhoud worden beschermd door patenten, handelsmerken en auteursrechten die eigendom zijn van
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