Description
dTTP, namely 2'-Deoxythymidine-5'-triphosphate, is used for molecular biological reactions, such as PCR, real-time PCR, RT-PCR, cDNA Synthesis, primer extension reaction, DNA sequencing, DNA labeling etc.
This product was in the form of sodium solution, prepared with ultrapure water, adjust pH 7.0 with a high purity NaOH solution. The concentration of dTTP is 100 mmol/L.
Ultra-high purity dTTP: >99% trisphosphate by HPLC; Free of DNase and RNase contamination.
Features
- Greater than 99% purity confirmed by HPLC
- Free of human and E.coli DNA
- Highly stable
Applications
- Long-range PCR (20 kb)
- cDNA synthesis and RT-PCR
- Real-time PCR
- Standard PCR
- High fidelity PCR
Specifications
Concentration | 100 mM |
CAS NO. | 18423-43-3 |
Form | Liquid |
Purity | >99% |
Label or Dye | Unlabeled |
For Use With (Application) | PCR Amplification |
Components
Components No. | Name | 10120ES74 | 10120ES80 | 10120ES96 | 10120ES97 |
10120 | dTTP Solution (100 mmol/L) | 400 μL | 1 mL | 25 mL | 400 mL |
Shipping and Storage
The product is shipped with dry ice and can be stored at -15℃ ~ -25℃ for 2 years. Please avoid repeated freeze-thaw.
[1] Zhang J, Zhang G, Zhang W, et al. Loss of RBMS1 promotes anti-tumor immunity through enabling PD-L1 checkpoint blockade in triple-negative breast cancer [published online ahead of print, 2022 May 10]. Cell Death Differ. 2022;10.1038/s41418-022-01012-0. doi:10.1038/s41418-022-01012-0(IF:15.828)
[2] Chai Q, Wang X, Qiang L, et al. A Mycobacterium tuberculosis surface protein recruits ubiquitin to trigger host xenophagy. Nat Commun. 2019;10(1):1973. Published 2019 Apr 29. doi:10.1038/s41467-019-09955-8(IF:11.878)
[3] Wang X, Ni J, You Y, et al. SNX10-mediated LPS sensing causes intestinal barrier dysfunction via a caspase-5-dependent signaling cascade. EMBO J. 2021;40(24):e108080. doi:10.15252/embj.2021108080(IF:11.598)
[4] Feng Y, Wang Y, Wang X, et al. Simultaneous epigenetic perturbation and genome imaging reveal distinct roles of H3K9me3 in chromatin architecture and transcription. Genome Biol. 2020;21(1):296. Published 2020 Dec 8. doi:10.1186/s13059-020-02201-1(IF:10.806)
[5] Tao X, Wan X, Wu D, Song E, Song Y. A tandem activation of NLRP3 inflammasome induced by copper oxide nanoparticles and dissolved copper ion in J774A.1 macrophage. J Hazard Mater. 2021;411:125134. doi:10.1016/j.jhazmat.2021.125134(IF:10.588)
[6] Alolga RN, Opoku-Damoah Y, Alagpulinsa DA, et al. Metabolomic and transcriptomic analyses of the anti-rheumatoid arthritis potential of xylopic acid in a bioinspired lipoprotein nanoformulation. Biomaterials. 2021;268:120482. doi:10.1016/j.biomaterials.2020.120482(IF:10.317)
[7] Mo X, Du S, Chen X, et al. Lactate Induces Production of the tRNA<sup>His</sup> Half to Promote B-lymphoblastic Cell Proliferation. Mol Ther. 2020;28(11):2442-2457. doi:10.1016/j.ymthe.2020.09.010(IF:8.986)
[8] Hao W, Han J, Chu Y, et al. Lower fluidity of supported lipid bilayers promotes neuronal differentiation of neural stem cells by enhancing focal adhesion formation. Biomaterials. 2018;161:106-116. doi:10.1016/j.biomaterials.2018.01.034(IF:8.806)
[9] Lin Z, Xia S, Liang Y, et al. LXR activation potentiates sorafenib sensitivity in HCC by activating microRNA-378a transcription. Theranostics. 2020;10(19):8834-8850. Published 2020 Jul 11. doi:10.7150/thno.45158(IF:8.579)
[10] Liu H, Xing R, Ou Z, et al. G-protein-coupled receptor GPR17 inhibits glioma development by increasing polycomb repressive complex 1-mediated ROS production. Cell Death Dis. 2021;12(6):610. Published 2021 Jun 12. doi:10.1038/s41419-021-03897-0(IF:8.469)
[11] Zhan T, Cui S, Shou H, et al. Transcriptome aberration in mice uterus associated with steroid hormone response and inflammation induced by dioxybenzone and its metabolites. Environ Pollut. 2021;286:117294. doi:10.1016/j.envpol.2021.117294(IF:8.071)
[12] Yu F, Zhu C, Ze S, et al. Design, Synthesis, and Bioevaluation of 2-Aminopteridin-7(8H)-one Derivatives as Novel Potent Adenosine A<sub>2A</sub> Receptor Antagonists for Cancer Immunotherapy. J Med Chem. 2022;65(5):4367-4386. doi:10.1021/acs.jmedchem.1c02199(IF:7.446)
[13] Zhu Y, Song D, Xu P, Sun J, Li L. A HD-ZIP III gene, PtrHB4, is required for interfascicular cambium development in Populus. Plant Biotechnol J. 2018;16(3):808-817. doi:10.1111/pbi.12830(IF:7.443)
[14] Liang R, Chen S, Jin Y, et al. The CXCL10/CXCR3 Axis Promotes Disease Pathogenesis in Mice upon CVA2 Infection. Microbiol Spectr. 2022;10(3):e0230721. doi:10.1128/spectrum.02307-21(IF:7.171)
[15] Xiao C, Sun D, Liu B, et al. Nitrate transporter NRT1.1 and anion channel SLAH3 form a functional unit to regulate nitrate-dependent alleviation of ammonium toxicity. J Integr Plant Biol. 2022;64(4):942-957. doi:10.1111/jipb.13239(IF:7.061)
[16] Zhao Y, Ma T, Zou D. Identification of Unique Transcriptomic Signatures and Hub Genes Through RNA Sequencing and Integrated WGCNA and PPI Network Analysis in Nonerosive Reflux Disease. J Inflamm Res. 2021;14:6143-6156. Published 2021 Nov 23. doi:10.2147/JIR.S340452(IF:6.922)
[17] Zhu Y, Ren C, Jiang D, et al. RPL34-AS1-induced RPL34 inhibits cervical cancer cell tumorigenesis via the MDM2-P53 pathway. Cancer Sci. 2021;112(5):1811-1821. doi:10.1111/cas.14874(IF:6.716)
[18] Qiao K, Tian Y, Hu Z, Chai T. Wheat Cell Number Regulator CNR10 Enhances the Tolerance, Translocation, and Accumulation of Heavy Metals in Plants. Environ Sci Technol. 2019;53(2):860-867. doi:10.1021/acs.est.8b04021(IF:6.653)
[19] Xie ST, Chen AX, Song B, et al. Suppression of microglial activation and monocyte infiltration ameliorates cerebellar hemorrhage induced-brain injury and ataxia. Brain Behav Immun. 2020;89:400-413. doi:10.1016/j.bbi.2020.07.027(IF:6.633)
[20] Zhang P, Lu S, Liu Z, et al. Transcriptomic and Metabolomic Profiling Reveals the Effect of LED Light Quality on Fruit Ripening and Anthocyanin Accumulation in Cabernet Sauvignon Grape. Front Nutr. 2021;8:790697. Published 2021 Dec 14. doi:10.3389/fnut.2021.790697(IF:6.576)
[21] Wang J, Hu R, Wang Z, et al. Establishment of Immortalized Yak Ruminal Epithelial Cell Lines by Lentivirus-Mediated SV40T and hTERT Gene Transduction. Oxid Med Cell Longev. 2022;2022:8128028. Published 2022 Mar 25. doi:10.1155/2022/8128028(IF:6.543)
[22] Lian B, Cai L, Zhang Z, et al. The anti-inflammatory effect of Pien Tze Huang in non-alcoholic fatty liver disease. Biomed Pharmacother. 2022;151:113076. doi:10.1016/j.biopha.2022.113076(IF:6.530)
[23] Ji L, Lin Z, Wan Z, et al. miR-486-3p mediates hepatocellular carcinoma sorafenib resistance by targeting FGFR4 and EGFR. Cell Death Dis. 2020;11(4):250. Published 2020 Apr 20. doi:10.1038/s41419-020-2413-4(IF:6.304)
[24] Chen SP, Zhu GQ, Xing XX, et al. LncRNA USP2-AS1 Promotes Hepatocellular Carcinoma Growth by Enhancing YBX1-Mediated HIF1α Protein Translation Under Hypoxia. Front Oncol. 2022;12:882372. Published 2022 May 25. doi:10.3389/fonc.2022.882372(IF:6.244)
[25] Pan Y, Hu GY, Jiang S, et al. Development of an Aerobic Glycolysis Index for Predicting the Sorafenib Sensitivity and Prognosis of Hepatocellular Carcinoma. Front Oncol. 2021;11:637971. Published 2021 May 18. doi:10.3389/fonc.2021.637971(IF:6.244)
[26] Chen X, He H, Xiao Y, et al. CXCL10 Produced by HPV-Positive Cervical Cancer Cells Stimulates Exosomal PDL1 Expression by Fibroblasts via CXCR3 and JAK-STAT Pathways. Front Oncol. 2021;11:629350. Published 2021 Aug 6. doi:10.3389/fonc.2021.629350(IF:6.244)
[27] Xu L, Wang J, Liu B, et al. HDAC9 Contributes to Serous Ovarian Cancer Progression through Regulating Epithelial-Mesenchymal Transition. Biomedicines. 2022;10(2):374. Published 2022 Feb 3. doi:10.3390/biomedicines10020374(IF:6.081)
[28] Xue X, Shu M, Xiao Z, et al. Lineage tracing reveals the origin of Nestin-positive cells are heterogeneous and rarely from ependymal cells after spinal cord injury. Sci China Life Sci. 2022;65(4):757-769. doi:10.1007/s11427-020-1901-4(IF:6.038)
[29] Zhang KK, Liu JL, Chen LJ, et al. Gut microbiota mediates methamphetamine-induced hepatic inflammation via the impairment of bile acid homeostasis. Food Chem Toxicol. 2022;166:113208. doi:10.1016/j.fct.2022.113208(IF:6.025)
[30] Zhao J, Li R, Li Y, Chen J, Feng F, Sun C. Broadly Antiviral Activities of TAP1 through Activating the TBK1-IRF3-Mediated Type I Interferon Production. Int J Mol Sci. 2021;22(9):4668. Published 2021 Apr 28. doi:10.3390/ijms22094668(IF:5.924)
[31] An L, Peng LY, Sun NY, et al. Tanshinone IIA Activates Nuclear Factor-Erythroid 2-Related Factor 2 to Restrain Pulmonary Fibrosis via Regulation of Redox Homeostasis and Glutaminolysis. Antioxid Redox Signal. 2019;30(15):1831-1848. doi:10.1089/ars.2018.7569(IF:5.828)
[32] Li D, He Q, Yang H, et al. Daily Dose of Bovine Lactoferrin Prevents Ethanol-Induced Liver Injury and Death in Male Mice by Regulating Hepatic Alcohol Metabolism and Modulating Gut Microbiota. Mol Nutr Food Res. 2021;65(18):e2100253. doi:10.1002/mnfr.202100253(IF:5.820)
[33] Chen LJ, He JT, Pan M, et al. Antibiotics Attenuate Methamphetamine-Induced Hepatotoxicity by Regulating Oxidative Stress and TLR4/MyD88/Traf6 Axis. Front Pharmacol. 2021;12:716703. Published 2021 Jul 26. doi:10.3389/fphar.2021.716703(IF:5.811)
[34] Liu P, Yang S, Wang Z, Dai H, Wang C. Feasibility and Mechanism Analysis of Shenfu Injection in the Treatment of Idiopathic Pulmonary Fibrosis. Front Pharmacol. 2021;12:670146. Published 2021 Jul 28. doi:10.3389/fphar.2021.670146(IF:5.811)
[35] Wu F, Zhao Y, Shao Q, et al. Ameliorative Effects of Osthole on Experimental Renal Fibrosis in vivo and in vitro by Inhibiting IL-11/ERK1/2 Signaling. Front Pharmacol. 2021;12:646331. Published 2021 May 13. doi:10.3389/fphar.2021.646331(IF:5.811)
[36] Qin Q, Yang B, Liu Z, Xu L, Song E, Song Y. Polychlorinated biphenyl quinone induced the acquisition of cancer stem cells properties and epithelial-mesenchymal transition through Wnt/β-catenin. Chemosphere. 2021;263:128125. doi:10.1016/j.chemosphere.2020.128125(IF:5.778)
[37] Cao L, Lu X, Wang G, et al. Maize ZmbZIP33 Is Involved in Drought Resistance and Recovery Ability Through an Abscisic Acid-Dependent Signaling Pathway. Front Plant Sci. 2021;12:629903. Published 2021 Apr 1. doi:10.3389/fpls.2021.629903(IF:5.754)
[38] Wei S, Zheng Q, Pan Y, Xu Y, Tang J, Cai X. Interplay between liver circadian rhythm and regeneration after PHx. Genomics. 2022;114(1):1-8. doi:10.1016/j.ygeno.2021.11.023(IF:5.736)
[39] Wang L, Liu XX, Yang YM, et al. RHBDF2 gene functions are correlated to facilitated renal clear cell carcinoma progression. Cancer Cell Int. 2021;21(1):590. Published 2021 Nov 4. doi:10.1186/s12935-021-02277-0(IF:5.722)
[40] Pan R, Lu Q, Ren C, et al. Anoctamin 5 promotes osteosarcoma development by increasing degradation of Nel-like proteins 1 and 2. Aging (Albany NY). 2021;13(13):17316-17327. doi:10.18632/aging.203212(IF:5.682)
[41] Cai D, Liu H, Wang J, et al. Balasubramide derivative 3C attenuates atherosclerosis in apolipoprotein E-deficient mice: role of AMPK-STAT1-STING signaling pathway. Aging (Albany NY). 2021;13(8):12160-12178. doi:10.18632/aging.202929(IF:5.682)
[42] Peng X, Zhang Y, Wan C, Gan Z, Chen C, Chen J. Antofine Triggers the Resistance Against Penicillium italicum in Ponkan Fruit by Driving AsA-GSH Cycle and ROS-Scavenging System. Front Microbiol. 2022;13:874430. Published 2022 Apr 12. doi:10.3389/fmicb.2022.874430(IF:5.640)
[43] Gong P, Kang J, Sadeghnezhad E, et al. Transcriptional Profiling of Resistant and Susceptible Cultivars of Grapevine (Vitis L.) Reveals Hypersensitive Responses to Plasmopara viticola. Front Microbiol. 2022;13:846504. Published 2022 Apr 25. doi:10.3389/fmicb.2022.846504(IF:5.640)
[44] Ma X, Chen J, Liu J, et al. IL-8/CXCR2 mediates tropism of human bone marrow-derived mesenchymal stem cells toward CD133<sup>+</sup> /CD44<sup>+</sup> Colon cancer stem cells. J Cell Physiol. 2021;236(4):3114-3128. doi:10.1002/jcp.30080(IF:5.546)
[45] Cao J, Shao H, Hu J, et al. Identification of invasion-metastasis associated MiRNAs in gallbladder cancer by bioinformatics and experimental validation. J Transl Med. 2022;20(1):188. Published 2022 Apr 28. doi:10.1186/s12967-022-03394-8(IF:5.531)
[46] Li J, Yang YL, Li LZ, et al. Succinate accumulation impairs cardiac pyruvate dehydrogenase activity through GRP91-dependent and independent signaling pathways: Therapeutic effects of ginsenoside Rb1. Biochim Biophys Acta Mol Basis Dis. 2017;1863(11):2835-2847. doi:10.1016/j.bbadis.2017.07.017(IF:5.476)
[47] Wan Y, Yang S, Peng M, et al. Controllable synthesis of biomimetic nano/submicro-fibrous tubes for potential small-diameter vascular grafts. J Mater Chem B. 2020;8(26):5694-5706. doi:10.1039/d0tb01002b(IF:5.344)
[48] Wu F, Shao Q, Xia Q, et al. A bioinformatics and transcriptomics based investigation reveals an inhibitory role of Huanglian-Renshen-Decoction on hepatic glucose production of T2DM mice via PI3K/Akt/FoxO1 signaling pathway. Phytomedicine. 2021;83:153487. doi:10.1016/j.phymed.2021.153487(IF:5.340)
[49] Yang L, Zhou R, Tong Y, et al. Neuroprotection by dihydrotestosterone in LPS-induced neuroinflammation. Neurobiol Dis. 2020;140:104814. doi:10.1016/j.nbd.2020.104814(IF:5.332)
[50] Cheng S, Wang D, Ke J, et al. Improved in vitro angiogenic behavior of human umbilical vein endothelial cells with oxidized polydopamine coating. Colloids Surf B Biointerfaces. 2020;194:111176. doi:10.1016/j.colsurfb.2020.111176(IF:5.268)
[51] Wang L, Ouyang S, Li B, Wu H, Wang F. GSK-3β manipulates ferroptosis sensitivity by dominating iron homeostasis. Cell Death Discov. 2021;7(1):334. Published 2021 Nov 3. doi:10.1038/s41420-021-00726-3(IF:5.241)
[52] Zhang D, Tao L, Xu N, et al. CircRNA circTIAM1 promotes papillary thyroid cancer progression through the miR-646/HNRNPA1 signaling pathway. Cell Death Discov. 2022;8(1):21. Published 2022 Jan 12. doi:10.1038/s41420-021-00798-1(IF:5.241)
[53] Zhong J, Qiu X, Yu Q, Chen H, Yan C. A novel polysaccharide from Acorus tatarinowii protects against LPS-induced neuroinflammation and neurotoxicity by inhibiting TLR4-mediated MyD88/NF-κB and PI3K/Akt signaling pathways. Int J Biol Macromol. 2020;163:464-475. doi:10.1016/j.ijbiomac.2020.06.266(IF:5.162)
[54] Yang Y, Wang J, Xu J, et al. Characterization of IL-22 Bioactivity and IL-22-Positive Cells in Grass Carp Ctenopharyngodon idella. Front Immunol. 2020;11:586889. Published 2020 Oct 6. doi:10.3389/fimmu.2020.586889(IF:5.085)
[55] He L, Gao K, Liu H, Wang J, Li X, He C. Smooth muscle cell-specific knockout of interferon gamma (IFN-γ) receptor attenuates intimal hyperplasia via STAT1-KLF4 activation [published online ahead of print, 2021 May 25]. Life Sci. 2021;119651. doi:10.1016/j.lfs.2021.119651(IF:5.037)
[56] Chen J, Dong Z, Lei Y, et al. Vitamin C suppresses toxicological effects in MO/MФ and IgM<sup>+</sup> B cells of Nile tilapia (Oreochromis niloticus) upon copper exposure. Aquat Toxicol. 2022;244:106100. doi:10.1016/j.aquatox.2022.106100(IF:4.964)
[57] Ma X, Xu J, Lu Q, et al. Hsa_circ_0087352 promotes the inflammatory response of macrophages in abdominal aortic aneurysm by adsorbing hsa-miR-149-5p. Int Immunopharmacol. 2022;107:108691. doi:10.1016/j.intimp.2022.108691(IF:4.932)
[58] Li S, Wang D, Wei P, et al. Elevated Natural Killer Cell-Mediated Cytotoxicity Is Associated with Cavity Formation in Pulmonary Tuberculosis Patients. J Immunol Res. 2021;2021:7925903. Published 2021 Oct 4. doi:10.1155/2021/7925903(IF:4.818)
[59] Tan XH, Zhang KK, Xu JT, et al. Luteolin alleviates methamphetamine-induced neurotoxicity by suppressing PI3K/Akt pathway-modulated apoptosis and autophagy in rats. Food Chem Toxicol. 2020;137:111179. doi:10.1016/j.fct.2020.111179(IF:4.679)
[60] Xu Y, Zhang G, Zou C, et al. Long non-coding RNA LINC01225 promotes proliferation, invasion and migration of gastric cancer via Wnt/β-catenin signalling pathway. J Cell Mol Med. 2019;23(11):7581-7591. doi:10.1111/jcmm.14627(IF:4.658)
[61] Shi YJ, Zhao QQ, Liu XS, et al. Toll-like receptor 4 regulates spontaneous intestinal tumorigenesis by up-regulating IL-6 and GM-CSF. J Cell Mol Med. 2020;24(1):385-397. doi:10.1111/jcmm.14742(IF:4.658)
[62] Zou Y, Xu X, Hu Q, Wang Y, Yang H, Zhang Z. Identification and diversity of fibrinogen-related protein (FREP) gene family in Haliotis discus hannai, H. rufescens, and H. laevigata and their responses to Vibrio parahemolyticus infection. Fish Shellfish Immunol. 2021;119:613-622. doi:10.1016/j.fsi.2021.10.041(IF:4.581)
[63] Cao L, Zhang P, Lu X, et al. Systematic Analysis of the Maize OSCA Genes Revealing ZmOSCA Family Members Involved in Osmotic Stress and ZmOSCA2.4 Confers Enhanced Drought Tolerance in Transgenic Arabidopsis. Int J Mol Sci. 2020;21(1):351. Published 2020 Jan 5. doi:10.3390/ijms21010351(IF:4.556)
[64] Ji Y, Yin W, Liang Y, Sun L, Yin Y, Zhang W. Anti-Inflammatory and Anti-Oxidative Activity of Indole-3-Acetic Acid Involves Induction of HO-1 and Neutralization of Free Radicals in RAW264.7 Cells. Int J Mol Sci. 2020;21(5):1579. Published 2020 Feb 25. doi:10.3390/ijms21051579(IF:4.556)
[65] Ren Z, Zhang Y, Cai T, et al. Dynamics of Microbial Communities across the Life Stages of Nilaparvata lugens (Stål). Microb Ecol. 2022;83(4):1049-1058. doi:10.1007/s00248-021-01820-w(IF:4.552)
[66] Wang C, Zheng D, Weng F, Jin Y, He L. Sodium butyrate ameliorates the cognitive impairment of Alzheimer's disease by regulating the metabolism of astrocytes. Psychopharmacology (Berl). 2022;239(1):215-227. doi:10.1007/s00213-021-06025-0(IF:4.530)
[67] Xia S, Wang X, Yue P, Li Y, Zhang D. Establishment of induced pluripotent stem cell lines from a family of an ARVC patient receiving heart transplantation in infant age carrying compound heterozygous mutations in DSP gene. Stem Cell Res. 2020;48:101977. doi:10.1016/j.scr.2020.101977(IF:4.495)
[68] Pan J, Ren Q, Yang Z, et al. The effect of melatonin on the mouse ameloblast-lineage cell line ALCs. Sci Rep. 2022;12(1):8225. Published 2022 May 17. doi:10.1038/s41598-022-11912-3(IF:4.380)
[69] Xu Z, Zhou Y, Nong Q, et al. LKB1 Differently Regulates Adipogenesis in Intramuscular and Subcutaneous Adipocytes through Metabolic and Cytokine-Related Signaling Pathways. Cells. 2020;9(12):2599. Published 2020 Dec 4. doi:10.3390/cells9122599(IF:4.366)
[70] Xu Y, Cai Z, Ba L, et al. Maintenance of Postharvest Quality and Reactive Oxygen Species Homeostasis of Pitaya Fruit by Essential Oil p-Anisaldehyde Treatment. Foods. 2021;10(10):2434. Published 2021 Oct 13. doi:10.3390/foods10102434(IF:4.350)
[71] Liu Q, Wang X, Qin J, et al. The ATP-Dependent Protease ClpP Inhibits Biofilm Formation by Regulating Agr and Cell Wall Hydrolase Sle1 in Staphylococcus aureus. Front Cell Infect Microbiol. 2017;7:181. Published 2017 May 15. doi:10.3389/fcimb.2017.00181(IF:4.300)
[72] Chen X, Niu X, Liu Y, et al. Long-term correction of haemophilia B through CRISPR/Cas9 induced homology-independent targeted integration [published online ahead of print, 2022 Jun 9]. J Genet Genomics. 2022;S1673-8527(22)00159-X. doi:10.1016/j.jgg.2022.06.001(IF:4.275)
[73] Zheng T, Guan L, Yu K, et al. Expressional diversity of grapevine 3-Hydroxy-3-methylglutaryl-CoA reductase (VvHMGR) in different grapes genotypes. BMC Plant Biol. 2021;21(1):279. Published 2021 Jun 19. doi:10.1186/s12870-021-03073-8(IF:4.215)
[74] Kang J, Gong P, Ge M, et al. "The PLCP gene family of grapevine (Vitis vinifera L.): characterization and differential expression in response to Plasmopara Viticola" [published correction appears in BMC Plant Biol. 2021 Nov 20;21(1):548]. BMC Plant Biol. 2021;21(1):499. Published 2021 Oct 30. doi:10.1186/s12870-021-03279-w(IF:4.215)
[75] Ge M, Zhong R, Sadeghnezhad E, et al. Genome-wide identification and expression analysis of magnesium transporter gene family in grape (Vitis vinifera). BMC Plant Biol. 2022;22(1):217. Published 2022 Apr 28. doi:10.1186/s12870-022-03599-5(IF:4.215)
[76] Zheng T, Dong T, Haider MS, Jin H, Jia H, Fang J. Brassinosteroid Regulates 3-Hydroxy-3-methylglutaryl CoA Reductase to Promote Grape Fruit Development. J Agric Food Chem. 2020;68(43):11987-11996. doi:10.1021/acs.jafc.0c04466(IF:4.192)
[77] Cao L, Lu X, Zhang P, Wang G, Wei L, Wang T. Systematic Analysis of Differentially Expressed Maize ZmbZIP Genes between Drought and Rewatering Transcriptome Reveals bZIP Family Members Involved in Abiotic Stress Responses. Int J Mol Sci. 2019;20(17):4103. Published 2019 Aug 22. doi:10.3390/ijms20174103(IF:4.183)
[78] Zhao R , Ji Y , Chen X , et al. Effects of a β-type glycosidic polysaccharide from Flammulina velutipes on anti-inflammation and gut microbiota modulation in colitis mice. Food Funct. 2020;11(5):4259-4274. doi:10.1039/c9fo03017d(IF:4.171)
[79] Bai RB, Zhang YJ, Fan JM, et al. Immune-enhancement effects of oligosaccharides from Codonopsis pilosula on cyclophosphamide induced immunosuppression in mice. Food Funct. 2020;11(4):3306-3315. doi:10.1039/c9fo02969a(IF:4.171)
[80] Ma L, Wu F, Shao Q, Chen G, Xu L, Lu F. Baicalin Alleviates Oxidative Stress and Inflammation in Diabetic Nephropathy via Nrf2 and MAPK Signaling Pathway. Drug Des Devel Ther. 2021;15:3207-3221. Published 2021 Jul 21. doi:10.2147/DDDT.S319260(IF:4.162)
[81] Zhou Y, Zhu Y, Dong X, et al. Exosomes Derived from Pancreatic Cancer Cells Induce Osteoclast Differentiation Through the miR125a-5p/TNFRSF1B Pathway. Onco Targets Ther. 2021;14:2727-2739. Published 2021 Apr 19. doi:10.2147/OTT.S282319(IF:4.147)
[82] Li D, Cui Y, Wang X, Liu F, Li X. Apple polyphenol extract alleviates lipid accumulation in free-fatty-acid-exposed HepG2 cells via activating autophagy mediated by SIRT1/AMPK signaling. Phytother Res. 2021;35(3):1416-1431. doi:10.1002/ptr.6902(IF:4.087)
[83] Wang X, Hu H, Wu Z, et al. Tissue-specific transcriptome analyses reveal candidate genes for stilbene, flavonoid and anthraquinone biosynthesis in the medicinal plant Polygonum cuspidatum. BMC Genomics. 2021;22(1):353. Published 2021 May 17. doi:10.1186/s12864-021-07658-3(IF:3.969)
[84] Tu S, Wu J, Chen L, et al. LncRNA CALB2 sponges miR-30b-3p to promote odontoblast differentiation of human dental pulp stem cells via up-regulating RUNX2. Cell Signal. 2020;73:109695. doi:10.1016/j.cellsig.2020.109695(IF:3.968)
[85] Ren B, Cao J, He Y, Yang S, Zhang J. Assessment on effects of transplastomic potato plants expressing Colorado potato beetle β-Actin double-stranded RNAs for three non-target pests. Pestic Biochem Physiol. 2021;178:104909. doi:10.1016/j.pestbp.2021.104909(IF:3.963)
[86] Xu Y, Zhang G, Zou C, et al. Long noncoding RNA DGCR5 suppresses gastric cancer progression by acting as a competing endogenous RNA of PTEN and BTG1. J Cell Physiol. 2019;234(7):11999-12010. doi:10.1002/jcp.27861(IF:3.923)
[87] Zhang G, Xu Y, Wang S, et al. LncRNA SNHG17 promotes gastric cancer progression by epigenetically silencing of p15 and p57. J Cell Physiol. 2019;234(4):5163-5174. doi:10.1002/jcp.27320(IF:3.923)
[88] Chen L, Song H, Luo Z, et al. PHLPP2 is a novel biomarker and epigenetic target for the treatment of vitamin C in pancreatic cancer. Int J Oncol. 2020;56(5):1294-1303. doi:10.3892/ijo.2020.5001(IF:3.899)
[89] Lin C, Chen J, Hu M, Zheng W, Song Z, Qin H. Sesamol promotes browning of white adipocytes to ameliorate obesity by inducing mitochondrial biogenesis and inhibition mitophagy via β3-AR/PKA signaling pathway. Food Nutr Res. 2021;65:10.29219/fnr.v65.7577. Published 2021 May 10. doi:10.29219/fnr.v65.7577(IF:3.894)
[90] Hu Q, Qin Q, Xu S, et al. Pituitary Actions of EGF on Gonadotropins, Growth Hormone, Prolactin and Somatolactins in Grass Carp. Biology (Basel). 2020;9(9):279. Published 2020 Sep 8. doi:10.3390/biology9090279(IF:3.796)
[91] Dong Y, Yang Y, Wang Z, et al. Inaccessibility to double-stranded RNAs in plastids restricts RNA interference in Bemisia tabaci (whitefly). Pest Manag Sci. 2020;76(9):3168-3176. doi:10.1002/ps.5871(IF:3.750)
[92] Wang X, Wu Z, Bao W, et al. Identification and evaluation of reference genes for quantitative real-time PCR analysis in Polygonum cuspidatum based on transcriptome data. BMC Plant Biol. 2019;19(1):498. Published 2019 Nov 14. doi:10.1186/s12870-019-2108-0(IF:3.670)
[93] Zhu Y, Du Q, Jiao N, et al. Catalpol ameliorates diabetes-induced testicular injury and modulates gut microbiota. Life Sci. 2021;267:118881. doi:10.1016/j.lfs.2020.118881(IF:3.647)
[94] You Y, Cui Y, Li Y, et al. Inhibition of MTA2 and MTA3 induces mesendoderm specification of human embryonic stem cells. Biochem Biophys Res Commun. 2021;552:142-149. doi:10.1016/j.bbrc.2021.03.030(IF:3.575)
[95] Cai Y, Liu Y, Sun Y, Ren Y. Mesenchyme homeobox 2 has a cancer-inhibiting function in breast carcinoma via affection of the PI3K/AKT/mTOR and ERK1/2 pathways. Biochem Biophys Res Commun. 2022;593:20-27. doi:10.1016/j.bbrc.2022.01.011(IF:3.575)
[96] Liu G, Liu Y, Niu B, et al. Genetic mutation of TRPV2 induces anxiety by decreasing GABA-B R2 expression in hippocampus. Biochem Biophys Res Commun. 2022;620:135-142. doi:10.1016/j.bbrc.2022.06.079(IF:3.575)
[97] Peng LY, An L, Sun NY, et al. Salvia miltiorrhiza Restrains Reactive Oxygen Species-Associated Pulmonary Fibrosis via Targeting Nrf2-Nox4 Redox Balance. Am J Chin Med. 2019;47(5):1113-1131. doi:10.1142/S0192415X19500575(IF:3.510)
[98] Chen J, Lei Y, Dong Z, et al. Toxicological damages on copper exposure to IgM<sup>+</sup> B cells of Nile tilapia (Oreochromis niloticus) and mitigation of its adverse effects by β-glucan administration. Toxicol In Vitro. 2022;81:105334. doi:10.1016/j.tiv.2022.105334(IF:3.500)
[99] Wan X, He X, Liu Q, Wang X, Ding X, Li H. Frequent and mild scrotal heat stress in mice epigenetically alters glucose metabolism in the male offspring. Am J Physiol Endocrinol Metab. 2020;319(2):E291-E304. doi:10.1152/ajpendo.00038.2020(IF:3.469)
[100] Li H, Zhang P, Lin H, Gao H, Yin J. ETC-1002 Attenuates Porphyromonas gingivalis Lipopolysaccharide-Induced Inflammation in RAW264.7 Cells via the AMPK/NF-κB Pathway and Exerts Ameliorative Effects in Experimental Periodontitis in Mice. Dis Markers. 2022;2022:8583674. Published 2022 Mar 16. doi:10.1155/2022/8583674(IF:3.434)
[101] Du Q, Zhang S, Li A, Mohammad IS, Liu B, Li Y. Astragaloside IV Inhibits Adipose Lipolysis and Reduces Hepatic Glucose Production via Akt Dependent PDE3B Expression in HFD-Fed Mice. Front Physiol. 2018;9:15. Published 2018 Jan 23. doi:10.3389/fphys.2018.00015(IF:3.394)
[102] Qi MM, He PZ, Zhang L, Dong WG. STAT3-mediated activation of mitochondrial pathway contributes to antitumor effect of dihydrotanshinone I in esophageal squamous cell carcinoma cells. World J Gastrointest Oncol. 2021;13(8):893-914. doi:10.4251/wjgo.v13.i8.893(IF:3.393)
[103] Liu Z, Lv X, Song E, Song Y. Fostered Nrf2 expression antagonizes iron overload and glutathione depletion to promote resistance of neuron-like cells to ferroptosis. Toxicol Appl Pharmacol. 2020;407:115241. doi:10.1016/j.taap.2020.115241(IF:3.347)
[104] Cao L, Lu X, Wang G, et al. Transcriptional regulatory networks in response to drought stress and rewatering in maize (Zea mays L.). Mol Genet Genomics. 2021;296(6):1203-1219. doi:10.1007/s00438-021-01820-y(IF:3.291)
[105] Nie K, Cai M. SNAT2/SLC38A2 Confers the Stemness of Gastric Cancer Cells via Regulating Glutamine Level. Dig Dis Sci. 2022;67(7):2948-2956. doi:10.1007/s10620-021-07110-2(IF:3.199)
[106] Zhou E, Yan F, Li B, et al. Molecular and functional characterization of IL-6 receptor (IL-6R) and glycoprotein 130 (gp130) in Nile tilapia (Oreochromis niloticus). Dev Comp Immunol. 2020;106:103629. doi:10.1016/j.dci.2020.103629(IF:3.192)
[107] Wang J, Wang W, Xu J, et al. Structural insights into the co-evolution of IL-2 and its private receptor in fish. Dev Comp Immunol. 2021;115:103895. doi:10.1016/j.dci.2020.103895(IF:3.192)
[108] Duan C, Xu X, Lu X, Wang L, Lu Z. RIP3 knockdown inhibits necroptosis of human intestinal epithelial cells via TLR4/MyD88/NF-κB signaling and ameliorates murine colitis. BMC Gastroenterol. 2022;22(1):137. Published 2022 Mar 26. doi:10.1186/s12876-022-02208-x(IF:3.067)
[109] Liu J, Liu Z, Li W, Zhang S. SOCS2 is a potential prognostic marker that suppresses the viability of hepatocellular carcinoma cells. Oncol Lett. 2021;21(5):399. doi:10.3892/ol.2021.12660(IF:2.967)
[110] Liu Z, Wang Y, Qin W, et al. Raloxifene alleviates amyloid-β-induced cytotoxicity in HT22 neuronal cells via inhibiting oligomeric and fibrillar species formation. J Biochem Mol Toxicol. 2019;33(11):e22395. doi:10.1002/jbt.22395(IF:2.965)
[111] Xu L, Xue T, Zhang J, Qu J. Knockdown of versican V1 induces a severe inflammatory response in LPS-induced acute lung injury via the TLR2-NF-κB signaling pathway in C57BL/6J mice. Mol Med Rep. 2016;13(6):5005-5012. doi:10.3892/mmr.2016.5168(IF:2.952)
[112] Mao K, Zhang X, Ali E, et al. Characterization of nitenpyram resistance in Nilaparvata lugens (Stål). Pestic Biochem Physiol. 2019;157:26-32. doi:10.1016/j.pestbp.2019.03.001(IF:2.870)
[113] Liao X, Xu PF, Gong PP, Wan H, Li JH. Current susceptibilities of brown planthopper Nilaparvata lugens to triflumezopyrim and other frequently used insecticides in China. Insect Sci. 2021;28(1):115-126. doi:10.1111/1744-7917.12764(IF:2.791)
[114] Cai T, Zhang Y, Liu Y, et al. Wolbachia enhances expression of NlCYP4CE1 in Nilaparvata lugens in response to imidacloprid stress. Insect Sci. 2021;28(2):355-362. doi:10.1111/1744-7917.12834(IF:2.791)
[115] Zhang J, Zhang B, Zhu F, Fu Y. Baseline sensitivity and fungicidal action of propiconazole against Penicillium digitatum. Pestic Biochem Physiol. 2021;172:104752. doi:10.1016/j.pestbp.2020.104752(IF:2.751)
[116] Lin K, Qu H, Tan Y, Deng T, Gao B, Wei N. Effects of the diphenylheptane extract of Alpinia officinarum rhizomes on ethanol-induced gastric ulcers in mice. Iran J Basic Med Sci. 2021;24(5):657-665. doi:10.22038/ijbms.2021.53644.12068(IF:2.699)
[117] Giri BR, Li H, Chen Y, Cheng G. Preliminary evaluation of neoblast-like stem cell factor and transcript expression profiles in Schistosoma japonicum. Acta Trop. 2018;187:57-64. doi:10.1016/j.actatropica.2018.07.022(IF:2.509)
[118] Xue Y, Fu W, Liu Y, et al. Ginsenoside Rb2 alleviates myocardial ischemia/reperfusion injury in rats through SIRT1 activation. J Food Sci. 2020;85(11):4039-4049. doi:10.1111/1750-3841.15505(IF:2.479)
[119] Gao LP, Du MJ, Lv JJ, Schmull S, Huang RT, Li J. Use of human aortic extracellular matrix as a scaffold for construction of a patient-specific tissue engineered vascular patch. Biomed Mater. 2017;12(6):065006. Published 2017 Oct 5. doi:10.1088/1748-605X/aa801b(IF:2.469)
[120] Sheng Z, Wang S, Zhang X, Li X, Li B, Zhang Z. Long-Term Exposure to Low-Dose Lead Induced Deterioration in Bone Microstructure of Male Mice. Biol Trace Elem Res. 2020;195(2):491-498. doi:10.1007/s12011-019-01864-7(IF:2.431)
[121] Zhang X, Li X, Sheng Z, et al. Effects of Combined Exposure to Cadmium and High-Fat Diet on Bone Quality in Male Mice. Biol Trace Elem Res. 2020;193(2):434-444. doi:10.1007/s12011-019-01713-7(IF:2.431)
[122] Wang W, Shao A, Amombo E, Fan S, Xu X, Fu J. Transcriptome-wide identification of MAPKKK genes in bermudagrass (Cynodon dactylon L.) and their potential roles in low temperature stress responses. PeerJ. 2020;8:e10159. Published 2020 Oct 28. doi:10.7717/peerj.10159(IF:2.379)
[123] Ding Y, Liu G, Zeng F, Yan Y, Jing H, Jiang X. Adrenal gland responses surgical castration and immunocastration by different compensatory manners to increase DHEA secretion [published online ahead of print, 2021 Dec 14]. Anim Biotechnol. 2021;1-8. doi:10.1080/10495398.2021.2007116(IF:2.271)
[124] Zhang LL, Zhang XY, Lu YY, Bi YD, Liu XL, Fang F. The Role of Autophagy in Murine Cytomegalovirus Hepatitis. Viral Immunol. 2021;34(4):241-255. doi:10.1089/vim.2020.0024(IF:2.257)
[125] Li X, Chen T, Han Y, et al. Potential role of Methoprene-tolerant (Met) in methyl farnesoate-mediated vitellogenesis in the Chinese mitten crab (Eriocheir sinensis). Comp Biochem Physiol B Biochem Mol Biol. 2021;252:110524. doi:10.1016/j.cbpb.2020.110524(IF:2.219)
[126] Chen T, Xu R, Sheng N, et al. Molecular evidence for farnesoic acid O-methyltransferase (FAMeT) involved in the biosynthesis of vitellogenin in the Chinese mitten crab Eriocheir sinensis. Anim Reprod Sci. 2021;234:106868. doi:10.1016/j.anireprosci.2021.106868(IF:2.145)
[127] Wu Y, Cui H, Zhang Y, et al. Inonotus obliquus extract alleviates myocardial ischemia/reperfusion injury by suppressing endoplasmic reticulum stress. Mol Med Rep. 2021;23(1):77. doi:10.3892/mmr.2020.11716(IF:2.100)
[128] Li X, Chen T, Jiang H, et al. Effects of methyl farnesoate on Krüppel homolog 1 (Kr-h1) during vitellogenesis in the Chinese mitten crab (Eriocheir sinensis). Anim Reprod Sci. 2021;224:106653. doi:10.1016/j.anireprosci.2020.106653(IF:1.660)
[129] Liu X, Pi B, Pu J, Cheng C, Fang J, Yu B. Genome-wide analysis of chloride channel-encoding gene family members and identification of CLC genes that respond to Cl<sup>-</sup>/salt stress in upland cotton. Mol Biol Rep. 2020;47(12):9361-9371. doi:10.1007/s11033-020-06023-z(IF:1.402)
[130] Li X, Lei Y, Yu Y, et al. Discovery and characterization of a novel splice variant of the p53 tumor suppressor gene in a human T cell leukemia cellline. Int J Clin Exp Pathol. 2020;13(5):1121-1135. Published 2020 May 1. (IF:0.252)
[131] Li X, Li M, Xu J, Zhang X, Xiao W, Zhang Z. Decreased Insulin Secretion but Unchanged Glucose Homeostasis in Cadmium-Exposed Male C57BL/6 Mice. J Toxicol. 2019;2019:8121834. Published 2019 Jun 20. doi:10.1155/2019/8121834(IF:0.000)