Description
UTP, Uridine-5'-triphosphate, can be used in a variety of molecular biology applications, such as in vitro transcription, RNA amplification, siRNA synthesis, etc. In addition, UTP is involved in galactose metabolism. The activated form of UDP-galactose is converted to UDP-glucose, which participates in the glycogen synthesis pathway.
This product is a transparent colorless aqueous solution prepared from UTP tris solution, and free from DNase and RNase contamination.
This product is produced in accordance with GMP process requirements and provided in liquid form.
Feature
- Validated, product-specific processes and analytical methods
- Product-specific stability
- Documentation follows applicable GMP guidelines
- AOF production process and raw materials (TSE & BSE)
- Nitrosamine statement
- Regulatory support documents available
- Large-scale production
- The increased IVT yield and the decreased dsRNA content under the optimized Tris NTP reaction system
Application
- RNA synthesis and amplification
- Building block for in vitro transcription
Specification
| CAS No | 63-39-8 (free acid) |
| Formula | C9H15N2O15P3 (free acid) |
| Molecular weight | 484.14 g/moL (free acid) |
| Purity(HPLC) | ≥ 99% |
| Content | 100 mM ± 3 mM |
| Structure |  |
Component
| Components No. | Name | 10654ES03 | 10654ES10 | 10654ES60 |
| 10654 | UTP Tris Solution GMP-grade (100 mM) | 1 mL | 10 mL | 100 mL |
Storage
The product should be stored at -25℃ ~ -15℃ for two years.
Figures
- Increased the IVT yield
Figure 1. The IVT yield was significantly increased under the optimized Tris NTP reaction system, compared with the sodium NTP reaction system.
- Decreased the dsRNA content
Figure 2. The content of dsRNA was significantly decreased under the optimized Tris NTP reaction system, compared with the sodium NTP reaction system. The content of dsRNA was detected by the Dot Blot method.