Description
Cas9 Nuclease is derived from the wild-type Streptococcus pyogenes and is an RNA-guided endonuclease that specifically cleaves double-stranded DNA (it can also cleave single-stranded DNA or RNA in the presence of a DNA PAM). The Cas9 cleavage site is located within the target sequence, three base pairs away from the PAM (NGG) region. Cas9 Nuclease has undergone codon optimization and design with a nuclear localization signal (NLS), and is expressed through recombinant expression in Escherichia coli. It exhibits high editing efficiency and can be used for gene modification in cells (such as hematopoietic stem cells, T cells, etc.), as well as for molecular diagnostics and pathogen detection.
Specifications
|
Cat.No. |
14701ES60 / 14701ES76 / 14701ES03 |
|
Size |
100 μg / 500 μg / 1 mg |
|
Source |
The Cas9 gene from Streptococcus pyogenes is expressed through recombinant expression in Escherichia coli. |
|
Concentration |
10 mg/mL |
|
Purity |
≥95% |
|
Tag |
His |
|
Endotoxin |
≤10 EU/mg |
Components
|
Components No. |
Name |
14701ES60 |
14701ES76 |
14701ES03 |
|
14701-A |
Cas9 Nuclease（10 mg/mL） |
10 μL |
50 μL |
100 μL |
|
14701-B |
10×Cas9 Nuclease Reaction Buffer |
500 μL |
1 mL |
1 mL |
Storage
This product should be stored at -25~-15℃ for 1 years.
Payment & Security
Your payment information is processed securely. We do not store credit card details nor have access to your credit card information.