Description
Exatecan（DXD）is a synthetic derivative of the naturally occurring compound camptothecin. it binds to the topoisomerase 1-DNA complex, preventing DNA re-ligation which results in the accumulation of DNA strand breaks and ultimately leads to cell death.
Specifications
|
Cat.No. |
31902ES60/31902ES80 |
|
Size |
100 μg/1 mg |
|
Source |
Monoclonal anti-DXD antibody, is produced from a hybridoma which was obtained from a mouse immunized with DXD. |
|
Buffer |
1×PBS, pH7.4. |
|
Type |
Monoclonal Antibody |
|
Isotype |
IgG1 |
|
Host |
Mouse |
|
Concentration |
1 mg/mL |
|
Purity |
＞98% as determined by reduced SDS-PAGE ＞98% as determined by non-reduced SDS-PAGE > 98% as determined by SEC-HPLC |
|
Activity |
EC50=41.4 ng/mL by ELISA |
|
Application |
ELISA |
Storage
This product should be stored at -25~-15℃ for one year, do not freeze.
Notes
- This product is for research use only.
- Please operate with lab coats and disposable gloves, for your safety.
Data
SDS-PAGE
Anti-DXD mouse mAb on SDS-PAGE under reduced condition. The purity is 98.2%；
Anti-DXD mouse mAb on SDS-PAGE under non-reduced condition. The purity is 98.4%.
SEC-HPLC
The purity of Anti-DXD mouse mAb is 99% as determined by SEC-HPLC.
ELISA Data
Dose response curve shows that the EC50 of Anti-DXD mouse mAb is 41.4 ng/mL.
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The product is for research purposes only and is not intended for therapeutic or diagnostic use in humans or animals. Products and content are protected by patents, trademarks, and copyrights owned by Yeasen Biotechnology. Trademark symbols indicate the country of origin, not necessarily registration in all regions.
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