Anti-MMAE Mouse mAb _ 31903ES

SKU: 31903ES60

Size: 100 μg
Price:
Sale price$395.00

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Description

MMAE, or monomethyl auristatin E, is a potent cytotoxic agent commonly used in the development of antibody-drug conjugates (ADCs) for targeted cancer therapy. It is an antimitotic agent which inhibits cell division by blocking the polymerization of tubulin.

Specifications

Cat.No.

31903ES60/31903ES80

Size

100 μg/1 mg

Source

Monoclonal anti-MMAE antibody, is produced from a hybridoma which was obtained from a mouse immunized with MMAE.

Buffer

1×PBS, pH7.4.

Type

Monoclonal Antibody

Isotype

IgG1

Host

Mouse

Concentration

1 mg/mL

Purity

94% as determined by reduced SDS-PAGE

97% as determined by non-reduced SDS-PAGE

> 98% as determined by SEC-HPLC

Activity

EC50=6.3 ng/mL by ELISA

Application

ELISA

Storage

This product should be stored at -25~-15℃ for one year, do not freeze.

 Notes

  1. This product is for research use only.
  2. Please operate with lab coats and disposable gloves, for your safety.

 

Data

SDS-PAGE

Anti-MMAE mouse mAb on SDS-PAGE under reduced condition. The purity is 94.7%

Anti-MMAE mouse mAb on SDS-PAGE under non-reduced condition. The purity is 97.6%.

 

SEC-HPLC

The purity of Anti-MMAE mouse mAb is 98% as determined by SEC-HPLC.

 

ELISA Data

Dose response curve shows that the EC50 of Anti-MMAE mouse mAb is 6.3 ng/mL.

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FAQ

The product is for research purposes only and is not intended for therapeutic or diagnostic use in humans or animals. Products and content are protected by patents, trademarks, and copyrights owned by Yeasen Biotechnology. Trademark symbols indicate the country of origin, not necessarily registration in all regions.

Certain applications may require additional third-party intellectual property rights.

Yeasen is dedicated to ethical science, believing our research should address critical questions while ensuring safety and ethical standards.