Description
Monomethyl auristatin F (MMAF) is a synthetic peptide analog of the natural compound dolastatin 10. MMAF is a microtubule inhibitor, disrupts the formation of microtubules. MMAF is often used in conjunction with monoclonal antibodies as part of an antibody-drug conjugate (ADC) therapy.
Specifications
|
Cat.No. |
31904ES60/31904ES80 |
|
Size |
100 μg/1 mg |
|
Source |
Monoclonal anti-MMAF antibody, is produced from a hybridoma which was obtained from a mouse immunized with MMAF. |
|
Buffer |
1×PBS, pH7.4. |
|
Type |
Monoclonal Antibody |
|
Isotype |
IgG1 |
|
Host |
Mouse |
|
Concentration |
1 mg/mL |
|
Purity |
＞92% as determined by reduced SDS-PAGE ＞98% as determined by non-reduced SDS-PAGE > 91% as determined by SEC-HPLC |
|
Activity |
EC50=13 ng/mL by ELISA |
|
Application |
ELISA |
Storage
This product should be stored at -25~-15℃ for one year, do not freeze.
Notes
- This product is for research use only.
- Please operate with lab coats and disposable gloves, for your safety.
Data
SDS-PAGE
Anti-MMAF mouse mAb on SDS-PAGE under reduced condition. The purity is 92.3%；
Anti-MMAF mouse mAb on SDS-PAGE under non-reduced condition. The purity is 98.5%.
SEC-HPLC
The purity of Anti-MMAF mouse mAb is 91.2% as determined by SEC-HPLC.
ELISA Data
Dose response curve shows that the EC50 of Anti-MMAF mouse mAb is 13 ng/mL.
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The product is for research purposes only and is not intended for therapeutic or diagnostic use in humans or animals. Products and content are protected by patents, trademarks, and copyrights owned by Yeasen Biotechnology. Trademark symbols indicate the country of origin, not necessarily registration in all regions.
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