Description
Forskolin is a natural diterpenoid product isolated from the Indian plant Coleus forskohlii that binds to the catalytic core of adenylyl cyclase (AC), which directly activates eukaryotic cell AC and increases cAMP levels in a variety of cells, and has been shown to activate all mammalian AC isoforms. In addition, Forskolin not only activates AC, but also interacts with certain other proteins, such as glucose transporters and ion channels. The interaction of forskolin with AC allows the development of affinity reagents for labeling or purifying enzymes. Studies have shown that forskolin can reduce intraocular pressure (IOP) in rabbits, monkeys, and humans, and that this effect is achieved by reducing intraocular fluid inflow without affecting outflow, therefore, forskolin can be used as a potential drug for the treatment of glaucoma.
Features
Purity≥97%
Standardized production, using factory mass production mode
Specifications
|
Cat.No. |
51001ES10/51001ES50/51001ES60 |
|
Size |
10 mg/50 mg/100 mg |
|
Synonym |
Forskolin, Colforsin, Coleonol |
|
Target |
adenylate cyclase |
|
CAS No. |
66575-29-9 |
|
Molecular formula |
C22H34O7 |
|
Molecular weight |
410.50 |
|
Appearance |
solid powder |
|
Purity |
≥97% |
|
Solubility |
Soluble in DMSO |
|
Structure |
 |
Components
|
Components No. |
Name |
51001ES10 |
51001ES50 |
51001ES60 |
|
51001 |
Forskolin |
10 mg |
50 mg |
100 mg |
Shipping and Storage
The Forskolin products should be stored at -15～-25℃ for 2 years. Avoid repeated freeze-thaw cycles.
Documents:
Safety Data Sheet
Manuals
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The product is for research purposes only and is not intended for therapeutic or diagnostic use in humans or animals. Products and content are protected by patents, trademarks, and copyrights owned by Yeasen Biotechnology. Trademark symbols indicate the country of origin, not necessarily registration in all regions.
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