Description
Y-27632 dihydrochloride (also known as Y27632 dihydrochloride, Y 27632 dihydrochloride, Y27632 2HCl) is a potent, selective, ATP-competitive ROCK inhibitor that acts on ROCK1 (p160ROCK) (Ki=140 nM) and ROCK-II (IC50=800 nM) and inhibits PRK2 activity. Y-27632 acts on human embryonic stem cells (hES) to significantly reduce apoptosis induced by cell isolation and improve cloning efficiency. Y-27632 can also promote the proliferation of human corneal epithelial cells cultured in vitro.
Features
Purity≥98%
Standardized production, using factory mass production mode
Specifications
|
Cat.No. |
52604ES08/52604ES10/52604ES25/52604ES50/52604ES60 |
|
Size |
5 mg/10 mg/25 mg/50 mg/100 mg |
|
Synonym |
Y-27632 2HCl |
|
Target |
ROCK-I; ROCK-II |
|
CAS No. |
129830-38-2 |
|
Molecular formula |
C14H21N3O • 2HCl |
|
Molecular weight |
320.26 |
|
Appearance |
solid powder |
|
Purity |
≥98% |
|
Solubility |
Soluble in H2O; soluble in DMSO |
|
Structure |
|
Components
|
Components No. |
Name |
52604ES08 |
52604ES10 |
52604ES25 |
52604ES50 |
52604ES60 |
|
52604 |
Y-27632 dihydrochloride |
5 mg |
10 mg |
25 mg |
50 mg |
100 mg |
Shipping and Storage
The Y-27632 dihydrochloride products should be stored at -15～-25℃ for 2 years. Avoid repeated freeze-thaw cycles.
Documents:
Safety Data Sheet
Manuals
Payment & Security
Your payment information is processed securely. We do not store credit card details nor have access to your credit card information.
Inquiry
You may also like
FAQ
The product is for research purposes only and is not intended for therapeutic or diagnostic use in humans or animals. Products and content are protected by patents, trademarks, and copyrights owned by Yeasen Biotechnology. Trademark symbols indicate the country of origin, not necessarily registration in all regions.
Certain applications may require additional third-party intellectual property rights.
Yeasen is dedicated to ethical science, believing our research should address critical questions while ensuring safety and ethical standards.