Description
Y-27632 (Y27632, Y 27632) is a potent, selective, ATP-competitive ROCK inhibitor, acts on ROCK1 (p160ROCK) (Ki=140 nM) and ROCK-II (IC50=800 nM), and inhibits PRK2 activity. The effect of Y-27632 on human embryonic stem cells (hES) significantly reduces cell separation-induced apoptosis and improves the efficiency of clone formation. Y-27632 can also promote the proliferation of human corneal epithelial cells cultured in vitro.
Features
Purity≥98%
Standardized production, using factory mass production mode
Specifications
|
Cat.No. |
53006ES03/53006ES08/53006ES10/53006ES50/53006ES60 |
|
Size |
1 mg/5 mg/10 mg/50 mg/100 mg |
|
Synonym |
Y27632; Y 27632 |
|
Target |
ROCK-I; ROCK-II |
|
CAS No. |
146986-50-7 |
|
Molecular formula |
C14H21N3O |
|
Molecular weight |
247.34 |
|
Appearance |
solid powder |
|
Purity |
≥98% |
|
Solubility |
soluble in DMSO |
|
Structure |
 |
Components
|
Components No. |
Name |
53006ES03 |
53006ES08 |
53006ES10 |
53006ES50 |
53006ES60 |
|
53006 |
Y-27632 |
1 mg |
5 mg |
10 mg |
50 mg |
100 mg |
Shipping and Storage
The Y-27632 products should be stored at -15～-25℃ for 2 years. Avoid repeated freeze-thaw cycles.
Documents:
Safety Data Sheet
Manuals
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The product is for research purposes only and is not intended for therapeutic or diagnostic use in humans or animals. Products and content are protected by patents, trademarks, and copyrights owned by Yeasen Biotechnology. Trademark symbols indicate the country of origin, not necessarily registration in all regions.
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