Gentamicin sulfate salt, a broad-spectrum aminoglycoside antibiotic, which has good resistance to many Gram-negative bacteria and Gram-positive bacteria capacity, even some β-Lactam sensitive anti vancomycin (VRE) enterococci, and some "superbacteria" resistant to glycopeptide antibiotics. Its antibacterial mechanism is that it binds to the 30S subunit of bacterial ribosome, leads to codon error, blocks the transport of peptidyl tRNA from site a to site P, and thus inhibits the synthesis of bacterial proteins.

Gentamicin sulfate is widely used in laboratories: 1) microbiological research, which is often used to screen sensitive bacteria in drug sensitivity experiments; 2) Inhibit bacterial contamination in cell culture, with an effective concentration of 0.5 - 50 µg/mL; 3) Molecular biology research is often used to selectively screen positive clones carrying gentamicin resistance genes, commonly used concentration: 15 µg/mL.

For other antibiotics, please refer to the related topic of Antibiotic User Manual.

Features

Potency ≥590 µg/mg

Standardized production, using factory mass production mode

Applications

Microbiological research, which is often used to screen sensitive bacteria in drug sensitivity experiments

Inhibit bacterial contamination in cell culture

Specifications

CAS NO.	1405-41-0
Molecular Fomular	C21H43N5O7·H2SO4
Molecular Weight	575.67 g/mol
Appearance	White to light yellow powder
Potency (dry basis)	≥590 μg/mg
Melting Point	218-237℃
Solubility	Dissolve in water (50 mg/mL), Almost insoluble in organic reagents such as ethanol
Structure

Components

Shipping and Storage

The Gentamicin Sulfate Salt products be stored at 2～8℃ for 2 years.

Documents:

Safety Data Sheet

60214_MSDS_HB250210_EN.pdf

Manuals

60214_Manual_HB250210_EN.pdf