Spectinomycin hydrochloride, an amino cyclic alcohol antibiotic, has a strong inhibitory effect on both Gram-positive and Gram-negative bacteria. Its antibacterial principle is that it can bind to the 30S subunit of bacterial ribosome and inhibit protein synthesis and extension by interfering with the translocation of peptide tRNA. The mutation of rpsE in ribosomal protein 5S gene can prevent the binding of spectinomycin hydrochloride and produce resistance to the antibiotic.

In cell culture, spectinomycin hydrochloride can be used as an antibacterial agent and a screening drug for screening resistant Escherichia coli or plant cells. It can be prepared into a storage solution of 10 mg/mL after 0.22 μM filter membrane, filter and sterilize, sub pack, and freeze at -25～-15℃.

For other antibiotics, please refer to the related topic of Antibiotic User Manual.

Features

Activity≥737 μg/mg

Standardized production, using factory mass production mode

Applications

A strong inhibitory effect on Gram-positive and Gram-negative bacteria

Screening drug for screening resistant Escherichia coli or plant cells

Specifications

CAS NO.	22189-32-8
Molecular Fomular	C14H24N2O7·2HCl
Molecular Weight	405.3 g/mol
Appearance	White crystal or powder
Activity	≥737 μg/mg
Melting Point	205-207℃
Solubility	Dissolve in water (～50 mg/mL), methanol，DMSO (～11 mg/mL)， ethanol (～0.3 mg/mL)
Structure

Components

Shipping and Storage

The Spectinomycin Hydrochloride products be stored at 2～8℃ for 2 years.

Documents:

Safety Data Sheet

60215_MSDS_HB250210_EN.pdf

Manuals

60215_Manual_HB250210_EN.pdf