Description
Rifampicin is a semi synthetic compound obtained from Amycolatopsis rifamycinica. It is an effective broad-spectrum antibacterial antibiotic. Rifampicin can highly bind to DNA dependent RNA polymerase (RNAP) and inhibit the activity of RNAP, thus inhibiting the protein synthesis of host bacteria. Rifampicin can also be used to treat tuberculosis and effectively inhibit intracellular pathogens, such as Mycobacterium M. tuberculosis and M. leprae. To avoid drug tolerance, rifampicin should be used in combination with other antibiotics.
50 mg rifampicin can be dissolved in 1 mL DMSO to prepare a storage solution of 50 mg/mL. after sub packaging, it can be frozen at -25~-15℃. When in use, it can be diluted to the working solution concentration with deionized water. The common working solution concentration is 10-50 ug/mL.
For other antibiotics, please refer to the related topic of Antibiotic User Manual.
Features
Assay≥95%
Standardized production, using factory mass production mode
Applications
An effective broad-spectrum antibacterial antibiotic
Used to treat tuberculosis and effectively inhibit intracellular pathogens
Specifications
CAS NO. |
13292-46-1 |
Molecular Fomular |
C43H58N4O12 |
Molecular Weight |
822.94 g/mol |
Appearance |
Orange red flake crystal or brick red crystal powder |
Assay |
≥95% |
Solubility |
100 mg/mL (DMSO), DMF, methanol (16 mg/mL, 25℃), chloroform (349 mg/mL, 25℃), acetone (14 mg/mL, 25℃), slightly soluble in water |
pH |
4.5 - 6.5 |
Structure |
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Components
Components No. |
Name |
60234ES03 |
60234ES08 |
60234 |
Rifampicin |
1 g |
5 g |
Shipping and Storage
The Rifampicin products be stored at -25~-15℃ for 2 years, protrcted from light.
Documents:
Safety Data Sheet
Manuals
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The product is for research purposes only and is not intended for therapeutic or diagnostic use in humans or animals. Products and content are protected by patents, trademarks, and copyrights owned by Yeasen Biotechnology. Trademark symbols indicate the country of origin, not necessarily registration in all regions.
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