Description
The human IL-2 protein, also known as interleukin-2, is an important cytokine that plays a vital role in regulating the immune system. It is produced by activated T cells and stimulates the proliferation and activation of various immune cells, such as T cells, B cells, and natural killer cells. IL-2 also promotes the development of immune memory and enhances the effectiveness of the immune response against infections and cancers. In addition, IL-2 has been used therapeutically in the treatment of certain diseases, such as cancer and autoimmune disorders, to boost the immune system.
Product information
|
Synonyms |
Interleukin-2; T-Cell Growth Factor; TCGF; Aldesleukin |
|
Uniprot No. |
P60568 |
|
Source |
HEK293 cells-derived human IL-2 protein, Ala21-Thr153, with N-terminal his tag. |
|
Molecular Weight |
Approximately 17.35 kDa. |
|
Purity |
> 90% as determined by SDS-PAGE. |
|
Biological Activity |
Human IL-2R immobilized on CM5 chip can bind human IL-2, His tag, with an affinity constant of 3.84 x 10-7 M as determined in a SPR assay (Biacore 8K). |
|
Endotoxin |
< 1 EU per 1μg of the protein by the LAL method. |
|
Formulation |
Lyophilized from a 0.2 μm filtered concentrated solution in PBS. |
|
Reconstitution |
Centrifuge tubes before opening. Dissolve lyophilized protein with PBS. Recommend to aliquot the protein into smaller quantities when first used and avoid repeated freeze-thaw cycles. |
Storage
The product should be stored at -25~-15℃ for 1 year from date of receipt.
2-7 days, 2 ~8 °C under sterile conditions after reconstitution.
3 months, -25~-15℃ under sterile conditions after reconstitution.
Notes
1.Please operate with lab coats and disposable gloves, for your safety.
2.This product is for research use only.