Description
IL-6 is similar to other interleukins in that it has a compact globular folding structure and is held in place by two disulfide bonds. The cysteine involved in forming these two disulfide bonds is highly conserved. IL-6, expressed by a variety of cells, regulates cell growth and differentiation in various tissues and is an important pro-inflammatory and immunomodulatory cytokine.
Product Properties
|
Synonyms |
Interleukin-6,BSF2,HSF,IFNB2 |
|
Uniprot No. |
P05231 |
|
Source |
Recombinant Human IL-6 Protein is expressed from E.coli without tag. It contains Val30-Met212. |
|
Molecular Weight |
The protein has a predicted 20.8 kDa same as Tris-Bis PAGE result. |
|
Purity |
> 95% as determined by SDS-PAGE. |
|
Biological Activity |
The ED50 as determined by a cell proliferation assay using human TF-1 cells is 0.1-0.5 ng/mL. |
|
Endotoxin |
< 1 EU per 1μg of the protein by the LAL method. |
|
Formulation |
Lyophilized from a 0.2 μm filtered concentrated solution in PBS. Normally 8% trehalose is added as protectant before lyophilization. |
|
Reconstitution |
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water. |
Shipping and Storage
The product should be stored at -25~-15℃ for 1 year from date of receipt.
2-7 days, 2 ~8 °C under sterile conditions after reconstitution.
3-6 months, -85~-65℃ under sterile conditions after reconstitution.
Recommend to aliquot the protein into smaller quantities when first used and avoid repeated freeze-thaw cycles.
Cautions
1.Please operate with lab coats and disposable gloves,for your safety.
2.This product is for research use only.
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The product is for research purposes only and is not intended for therapeutic or diagnostic use in humans or animals. Products and content are protected by patents, trademarks, and copyrights owned by Yeasen Biotechnology. Trademark symbols indicate the country of origin, not necessarily registration in all regions.
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