Description
The interleukin (IL)-1 cytokine family currently consists of 11 members with pleiotropic functions in inflammation and cancer.IL-1α and IL-1β were the first members of the IL-1 family to be described, and they both signal through the same receptor, IL-1R.
Product Properties
|
Synonyms |
Interleukin-1 alpha; IL-1 alpha; Hematopoietin-1; IL1A; IL1F1; IL-1 ALPHA; IL1; IL-1A; IL1 |
|
Species |
Mouse |
|
Source |
HEK293 |
|
Sequence |
Ser115-Ser270 |
|
Accession |
P01582 |
|
Tag |
C-His |
|
Molecular Weight |
The protein has a predicted MW of 19.08 kDa. Due to glycosylation, the protein migrates to 24-30 kDa based on Bis-Tris PAGE result. |
|
Endotoxin |
< 1 EU/μg by the LAL method. |
|
Purity |
> 95% as determined by Bis-Tris PAGE and HPLC |
|
Activity |
SPR Data: Mouse IL-1R1, His Tag immobilized on CM5 Chip can bind Mouse IL-1 alpha, His Tag with an affinity constant of 51.22 nM as determined in SPR assay. |
|
Formulation |
Lyophilized from 0.22 μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
|
Appearance |
Lyophilized powder |
Shipping and Storage
-25 ~ -15 ° C storage, 1 year expiration date after receipt. After re-solution, store at 2 ~8 °C, 7 days expiration date. After re-dissolution, store at -85~-65°C, 3 months expiration date.
Compounding method
Centrifuge before opening the lid. Use distilled water to reconstitute lyophilized proteins at reconstitution concentrations greater than 100 μg/mL. it is recommended that proteins be portioned out for each experimental dosage upon first use to avoid repeated freeze-thawing.
Cautions
1. For your safety and health, please wear lab coat and disposable gloves.
2. This product is for scientific research purposes only.
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The product is for research purposes only and is not intended for therapeutic or diagnostic use in humans or animals. Products and content are protected by patents, trademarks, and copyrights owned by Yeasen Biotechnology. Trademark symbols indicate the country of origin, not necessarily registration in all regions.
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