Description
Interleukin 6 (IL-6) is a pleiotropic cytokine that plays an important role in host defense by regulating immune and inflammatory responses.IL-6 is produced by T cells, monocytes, fibroblasts, endothelial cells, and keratin-forming cells, and has a variety of biological functions. It stimulates B cell differentiation and antibody production, synergizes with IL-3 in megakaryocyte development and platelet production, induces the expression of hepatic acute-phase proteins, and regulates bone metabolism.IL-6 signals through the IL-6 receptor system, which consists of two chains, IL-6Rα and gp130.
This product is available as Liquid, high activity, high purity, low endotoxin, No labeling.
Product Properties
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Synonyms |
Mouse B-cell differentiation factor; B-cell stimulatory factor 2; BSF2; BSF-2; CDF; CTL differentiation factor ; HSF; hybridoma growth factor; IFNB2; IFN-beta-2; IL6; IL-6; Interferon beta-2; interleukin 6 |
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Species |
Mouse |
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Source |
HEK293 Ceslls |
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Sequence |
Phe25-Thr211 |
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Accession |
P08505 |
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Tag |
No |
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Predicted molecularmass |
21.7 KDa |
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Endotoxin |
<0.010 EU per 1 μg of the protein by the LAL method |
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Purity |
> 95%, determined by SDS-PAGE |
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Activity |
Measured in a cell proliferation assay using T1165.85.2.1 mouse plasmacytoma cells. The ED50 for this effect is 0.02-0.06 ng/mL. |
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Formulation |
Dissolved in sterile PBS buffer. |
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Appearance |
Liquid |
Shipping and Storage
-85~-65℃ storage, valid for 1 year after receipt.
Avoid repeated freezing and thawing, centrifuge before opening the vial. It is recommended to aliquot for one experimental use, after aliquoting, freeze at -80℃.
Cautions
1. For your safety and health, please wear lab coat and disposable gloves.
2. This product is for scientific research purposes only.
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FAQ
The product is for research purposes only and is not intended for therapeutic or diagnostic use in humans or animals. Products and content are protected by patents, trademarks, and copyrights owned by Yeasen Biotechnology. Trademark symbols indicate the country of origin, not necessarily registration in all regions.
Certain applications may require additional third-party intellectual property rights.
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