Description
Description
The human BAFF protein, or B-cell activating factor, is a crucial cytokine that plays a significant role in regulating the immune system and promoting B-cell survival and maturation. BAFF is primarily produced by immune cells, including monocytes, macrophages, and dendritic cells. It binds to specific receptors on B cells, allowing their development and preventing apoptosis (cell death). BAFF also influences the production of antibodies and helps regulate the balance of different B-cell subsets.
Product information
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Synonyms |
BLyS, CD257, TNFSF13B, TNFSF20, TALL-1, BLys, THANK, BAFFB-cell activating factor, ZTNF4 |
|
Uniprot No. |
Q9Y275 |
|
Source |
HEK293 cells-derived human BAFF protein, Ala134-Leu285, with N-terminal His tag. |
|
Molecular Weight |
Approximately 18.12 kDa. |
|
Purity |
> 90% as determined by SDS-PAGE. |
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Biological Activity |
Human BCMA, His tag immobilized on CM5 chip can bind BAFF, His tag, with an affinity constant of 1.55 x 10-9 M as determined in a SPR assay (Biacore 8K). |
|
Endotoxin |
< 0.1 EU per 1μg of the protein by the LAL method. |
|
Formulation |
Lyophilized from a 0.2 μm filtered concentrated solution in PBS. |
|
Reconstitution |
Centrifuge tubes before opening. Dissolve lyophilized protein with PBS. Recommend to aliquot the protein into smaller quantities when first used and avoid repeated freeze-thaw cycles. |
Storage
The product should be stored at -25~-15℃ for 1 year from date of receipt.
2-7 days, 2 ~8 °C under sterile conditions after reconstitution.
3 months, -25~-15℃ under sterile conditions after reconstitution.
Notes
1.Please operate with lab coats and disposable gloves, for your safety.
2.This product is for research use only.
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