Description
Description
Noggin is a bone morphogenetic protein (BMP) antagonist expressed in Spemann's organizer. It inhibits TGF-β family ligands and preventing them from binding to their corresponding receptors.
Product information
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Synonyms |
NOG, SYM1, symphalangism 1 (proximal), synostoses (multiple) syndrome 1, SYNS1 |
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Uniprot No. |
Q13253 |
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Source |
HEK293 cells -derived human Noggin protein, Gln28-Cys232, with a His tag at the C-terminal |
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Molecular Weight |
The protein migrates as 30 KDa under reducing (R) condition (SDS-PAGE) . |
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Activity |
Measured by its ability to bind BMP2 with Elisa method . Optimal concentrations should be determined by each laboratory for each application |
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Purity |
> 95% as determined by SDS-PAGE. |
|
Endotoxin |
<1.0 EU per 1μg of the protein by the LAL method. |
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Formulation |
Lyophilized from a 0.2 μm filtered solution in PBS. |
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Reconstitution |
It is recommended that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute the lyophilized powder in ddH2O or PBS up to 100 μg/ml. |
Storage
The product should be stored at -85~-65℃ for 1 year from date of receipt.
Notes
1.Please operate with lab coats and disposable gloves,for your safety.
2.This product is for research use only.