Description
CD2-like receptor activating cytotoxic cells (CRACC), also known as CS1, SLAMF7, and CD319, is a 65-75 kDa type I transmembrane glycoprotein in the SLAM subgroup of the CD2 family. Within the ECD, human CRACC shares 54% and 52% aa sequence identity with mouse and rat CRACC, respectively. There are seven known isoforms of CRACC which are distinguished by deletions and/or substitutions in both their ECD and cytoplasmic domains. CRACC is expressed on the surface of NK cells, CD8+ T cells, activated B cells, and mature dendritic cells.
Specifications
|
Synonyms |
CD2 subset 1; CRACC; CD319; CS1; Novel Ly9; SLAMF7; 19A; FOAP-12 |
|
Uniprot No. |
Q9NQ25-1 |
|
Source |
Recombinant Biotinylated Human SLAMF7/CRACC/CD319 Protein is expressed from HEK293 Cells with His tag and Avi tag at the C-terminal. It contains Ser23-Met226. |
|
Source |
The protein has a predicted MW of 25.3 kDa. Due to glycosylation, the protein migrates to 40-60 kDa based on Tris-Bis PAGE result. |
|
Physical Appearance |
Sterile Filtered White lyophilized (freeze-dried) powder. |
|
Purity |
> 95% as determined by SDS-PAGE and HPLC |
|
Endotoxin |
< 1.0 EU per 1μg of the protein by the LAL method. |
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Formulation |
Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 5% trehalose is added as protectant before lyophilization. |
|
Reconstitution |
Centrifuge tubes before opening. Reconstituting to a concentration more than 100μg/mL is recommended. Dissolve the lyophilized protein in distilled water. |
Storage
The products are shipped with ice pack and can be stored at -20℃ for 1 year.
2-7 days, 2 to 8 °C under sterile conditions after reconstitution.
3 -6 months, -20 to -80°C under sterile conditions after reconstitution.
Recommend to aliquot the protein into smaller quantities for optimal storage. Please avoid freeze-thaw cycles.
Note
1.For your safety and health, please wear lab coats and disposable gloves for operation.
2.For research use only!
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The product is for research purposes only and is not intended for therapeutic or diagnostic use in humans or animals. Products and content are protected by patents, trademarks, and copyrights owned by Yeasen Biotechnology. Trademark symbols indicate the country of origin, not necessarily registration in all regions.
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