Description
Mesothelin is normally expressed on mesothelial cells in the pleura, pericardium, and peritoneum as well as in the developing and postnatal pancreas. It is upregulated in mesotheliomas and a range of carcinomas and adenomas. Mesothelin promotes tumor cell proliferation, migration, anchorage-independent growth, and tumor progression.
Specifications
|
Synonyms |
MSLN; CAK1; Mesothelin; MPF; MPFSMRP; SMR |
|
Uniprot No. |
Q13421-2 |
|
Source |
Recombinant FITC-Labeled Human MSLN/Mesothelin Protein is expressed from HEK293 Cells with His tag and Avi tag at the C-terminal. It contains Glu296-Gly580 |
|
Molecular Weight |
The protein has a predicted MW of 35.2 kDa. Due to glycosylation, the protein migrates to 40-50 kDa based on Tris-Bis PAGE result. |
|
Purity |
> 95% as determined by SDS-PAGE. |
|
Endotoxin |
< 1.0 EU per 1μg of the protein by the LAL method. |
|
Formulation |
Supplied as from 0.22 μm filtered solution in PBS (pH 7.4). |
Storage
The products are shipped with ice pack and can be stored at -80℃ for 1 year.
Recommend to aliquot the protein into smaller quantities for optimal Storage. Please avoid freeze-thaw cycles.
Note
1.For your safety and health, please wear lab coats and disposable gloves for operation.
2.For research use only!
Product Data
Tris-Bis PAGE
FACS Data
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The product is for research purposes only and is not intended for therapeutic or diagnostic use in humans or animals. Products and content are protected by patents, trademarks, and copyrights owned by Yeasen Biotechnology. Trademark symbols indicate the country of origin, not necessarily registration in all regions.
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