Description
Mesothelin is derived from a precursor-Megakaryocyte Potentiating Factor (MPF). MPF is a cytokine that potentiates IL-3 induced megakaryocyte colony formation. Mesothelin is normally expressed on mesothelial cells in the pleura, pericardium, and peritoneum as well as in the developing and postnatal pancreas. Mesothelin promotes tumor cell proliferation, migration, anchorage-independent growth, and tumor progression.
Specifications
|
Synonyms |
MSLN, CAK1, Mesothelin, MPF, MPFSMRP, SMR |
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Accession |
|
|
Source |
HEK293 Cells-derived Human MSLN/Mesothelin Protein, Glu296-Asp580 with hFc tag at the C-terminal |
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Molecular Weight |
The protein has a predicted MW of 35.88 kDa. Due to glycosylation, the protein migrates to 43-53 kDa based on Tris-Bis PAGE result. |
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Purity |
> 95% by SDS-PAGE and HPLC. |
|
Endotoxin |
< 1.0 EU per 1μg of the protein by the LAL method. |
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Formulation |
Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
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Reconstitution |
Centrifuge tubes before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water. |
Storage
The product should be stored at -25~-15℃ for 1 year.
2-7 days, 2 ~8 °C under sterile conditions after reconstitution.
3 months, -25~-15℃ under sterile conditions after reconstitution.
Recommend to aliquot the protein into smaller quantities when first used and avoid repeated freeze-thaw cycles.
Note
1.Please operate with lab coats and disposable gloves,for your safety.
2.This product is for research use only.
Product Data
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The product is for research purposes only and is not intended for therapeutic or diagnostic use in humans or animals. Products and content are protected by patents, trademarks, and copyrights owned by Yeasen Biotechnology. Trademark symbols indicate the country of origin, not necessarily registration in all regions.
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