Description
VEGFR2 is a receptor for vascular endothelial growth factor (VEGF) that mediates virtually all known cellular responses to VEGF. VEGFR2 is mainly expressed in endothelial cells and is up-regulated in tumor vascular system. Inhibition of VEGFR2 activity and its downstream signal is an important target for the treatment of angiogenic diseases.
Specifications
|
Synonyms |
KDR;Flk-1 |
|
Uniprot No. |
P35968 |
|
Source |
Recombinant Human VEGFR2 Protein is expressed from HEK293 Cells with His tag at the C-terminal. It contains Ala 20-Glu 764. |
|
Molecular Weight |
The protein has a predicted MW of 85.22 kDa. And it migrates as 130 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation. |
|
Purity |
> 95% as determined by SDS-PAGE. |
|
Endotoxin |
<0.1 EU per 1μg of the protein by the LAL method. |
|
Formulation |
Lyophilized from 0.22 μm filtered solution in PBS (pH 7.4). |
|
Reconstitution |
Centrifuge tubes before opening. Dissolve lyophilized protein with sterile PBS to ensure the concentration is greater than 100 ug/mL. |
Storage
The product should be stored at -25~-15℃ for 1 year from date of receipt.
2-7 days, 2 ~8 °C under sterile conditions after reconstitution.
3 months, -25~-15℃ under sterile conditions after reconstitution.
Recommend to aliquot the protein into smaller quantities when first used and avoid repeated freeze-thaw cycles.
Note
1.Please operate with lab coats and disposable gloves,for your safety.
2.This product is for research use only.
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The product is for research purposes only and is not intended for therapeutic or diagnostic use in humans or animals. Products and content are protected by patents, trademarks, and copyrights owned by Yeasen Biotechnology. Trademark symbols indicate the country of origin, not necessarily registration in all regions.
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