Description
CD30 is a cell membrane protein of the tumor necrosis factor receptor family that regulates proliferation/apoptosis and antibody responses, and is expressed by activated T cells and B cells. CD30 is considered to be a specific diagnostic biomarker for anaplastic large cell lymphoma (ALCL) and classical Hodgkin lymphoma (cHL), and also a biomarker for antibody-drug conjugate targeted therapy.
Specifications
|
Synonyms |
TNFRSF8,CD30,D1S166E,Ki-1 |
|
Uniprot No. |
P28908 |
|
Source |
Human CD30 Protein is expressed from HEK293 Cells with His tag at the C-terminal. It contains Phe 19 - Lys 379 |
|
Source |
The protein has a predicted MW of 39 kDa. And it migrates as 40-50 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation. |
|
Purity |
> 95% as determined by SDS-PAGE. |
|
Endotoxin |
<1 EU per 1μg of the protein by the LAL method. |
|
Formulation |
Lyophilized from 0.22 μm filtered solution in PBS (pH 7.4). |
|
Reconstitution |
Centrifuge tubes before opening. The concentration of protein solution used for lyophilization is generally 1mg/mL. Dissolve lyophilized protein with sterile water to ensure the concentration is greater than 100 μg/mL. |
Storage
The product should be stored at -25~-15℃ for 1 year.
2-7 days, 2 ~8 °C under sterile conditions after reconstitution.
3 months, -25~-15℃ under sterile conditions after reconstitution.
Recommend to aliquot the protein into smaller quantities when first used and avoid repeated freeze-thaw cycles.
Note
1.Please operate with lab coats and disposable gloves,for your safety.
2.This product is for research use only.
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The product is for research purposes only and is not intended for therapeutic or diagnostic use in humans or animals. Products and content are protected by patents, trademarks, and copyrights owned by Yeasen Biotechnology. Trademark symbols indicate the country of origin, not necessarily registration in all regions.
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