描述
Interleukin 15 (IL-15) is an immunomodulatory cytokine that stimulates the proliferation of T-lymphocytes.IL-15 exerts its biological activity primarily on T-cells. It is also essential for the development, survival, and activation of NK cells.Increased IL-15 expression has been associated with rheumatoid arthritis, inflammatory bowel disease, and diseases associated with retroviral HIV and HTLV-I.
This Recombinant Mouse IL-15 is supplied as Lyophilized powder with high activity, high purity and low endotoxin.
Product Properties
|
Synonyms |
IL15, Interleukin-15, IL-15, MGC9721 |
|
Source |
E.coli |
|
Sequence |
Asn49-Ser162 |
|
Accession |
P48346 |
|
Endotoxin |
< 1.0 EU/μg by the LAL method. |
|
Purity |
> 95%，determined by SDS-PAGE |
|
Biological Activity |
Measure by its ability to induce CTLL-2 cells proliferation. The ED50 for this effect is <10 ng/mL. The specific activity of recombinant mouse IL-15 is approximately >1x 10⁵ IU/mg. |
|
Formulation |
Lyophilized from a 0.22 μm filtered solution of 1×PBS, pH 7.4. |
|
Tag |
6His |
|
Physical Appearance |
Lyophilized powder |
Shipping and Storage
-25 ~ -15 ° C storage, 1 year expiration date after receipt.
After re-dissolving, store at 2 ~8 °C, 7 days expiration date. After re-dissolution, store at -25~-15 °C, 3 months expiration date.
Compounding method
Centrifuge at 3000 rpm for 5 minutes before uncapping. It is recommended that lyophilized proteins be reconstituted in NO bacterial H2O to a concentration of no less than 100 μg/mL and that the stock solution be incubated at room temperature for at least 20 minutes to ensure adequate re-solubilization. Do not vortex! Vigorous shaking may impair the biological activity of the protein. For long-term storage, it is recommended to add a carrier protein or stabilizer (e.g., 0.1% BSA, 5% HSA, 10% FBS, or 5% alginate), and to dispense the re-solubilized protein solution as needed to avoid repeated freezing and thawing.
Cautions
1. For your safety and health, please wear lab coat and disposable gloves.
2. This product is for scientific research purposes only.
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The product is for research purposes only and is not intended for therapeutic or diagnostic use in humans or animals. Products and content are protected by patents, trademarks, and copyrights owned by Yeasen Biotechnology. Trademark symbols indicate the country of origin, not necessarily registration in all regions.
Certain applications may require additional third-party intellectual property rights.
Yeasen is dedicated to ethical science, believing our research should address critical questions while ensuring safety and ethical standards.