描述
Interleukin 19 (IL-19) is a glycosylated protein secretion that exists as a monomer.IL-19 is mainly produced by monocytes and its expression is induced by LPS, IL-4, and GM-CSF.IL-19 is expressed at a low level in B-cells.IL-19, IL-20, and IL-24 are members of the IL-20 subfamily of the IL-10 family, and they can all bind IL-20 receptors and cause activation of the STAT3 signaling pathway.IL20R2 can be paired with IL20R1 or IL22R1 to form either a type I IL20R complex or a type II IL20R complex.IL-20 and IL-24 both have signaling pathways, whereas IL-19 can only signal through the IL-20 receptor complex.
This product is available as Liquid, high purity, high activity, low endotoxin, No labeling.
Product Properties
|
Synonyms |
IL-10C; IL19; IL-19; interleukin 19; MDA1; melanoma differentiation associated protein-like protein; |
|
Species |
Mouse |
|
Source |
HEK293 Ceslls |
|
Sequence |
Leu25-Ala176 |
|
Accession |
Q8CJ70 |
|
Tag |
No |
|
Predicted molecularmass |
17.6 kDa |
|
Endotoxin |
<0.010 EU per 1 μg of the protein by the LAL method |
|
Purity |
> 95%, determined by SDS-PAGE |
|
Activity |
Measured in a cell proliferation assay using BaF3 mouse pro-B cells transfected with human IL-20 R alpha and human IL-20 R beta. The EC50 for this effect is 4-20 pg/mL. |
|
Formulation |
Dissolved in sterile PBS buffer. |
|
Appearance |
Liquid |
Shipping and Storage
-85~-65℃ storage, valid for 1 year after receipt.
Avoid repeated freezing and thawing, centrifuge before opening the vial. It is recommended to aliquot for one experimental use, after aliquoting, freeze at -80℃.
Cautions
1. For your safety and health, please wear lab coat and disposable gloves.
2. This product is for scientific research purposes only.
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The product is for research purposes only and is not intended for therapeutic or diagnostic use in humans or animals. Products and content are protected by patents, trademarks, and copyrights owned by Yeasen Biotechnology. Trademark symbols indicate the country of origin, not necessarily registration in all regions.
Certain applications may require additional third-party intellectual property rights.
Yeasen is dedicated to ethical science, believing our research should address critical questions while ensuring safety and ethical standards.