描述
Tumor necrosis factor alpha (TNF-α ), also known as malathin and TNFSF2, is the prototypical ligand of the TNF superfamily. It is a pleiotropic molecule that plays a central role in inflammation, immune system development, apoptosis and lipid metabolism. In ECD, mouse TNF-α shares 94% amino acid sequence identity with rat, and 70%-77% amino acid sequence identity with bovine, canine, cotton rat, equine, feline, human, porcine, rat, and rhesus monkey TNF-α is produced by a wide variety of immune cells, epithelial, endothelial, and tumor cells.
This product is supplied as Liquid, high activity, high purity, low endotoxin, No labeling.
Product Properties
|
Synonyms |
TNF; TNF, monocyte-derived; TNFA; TNF-A; TNFalpha; TNF-alpha; TNFATNF; TNFG1F; TNFSF1A; TNFSF2; tumor necrosis factor alpha; |
|
Species |
Mouse |
|
Source |
HEK293 Ceslls |
|
Sequence |
Leu80-Leu235 |
|
Accession |
P06804 |
|
Tag |
No |
|
Predicted molecularmass |
17.3 KDa |
|
Endotoxin |
<0.010 EU per 1 μg of the protein by the LAL method |
|
Purity |
> 95%, determined by SDS-PAGE |
|
Activity |
Measured in a cytotoxicity assay using L929 mouse fibroblast cells .The ED50 for this effect is 8-50 pg/mL. |
|
Formulation |
Dissolved in sterile PBS buffer. |
|
Appearance |
Liquid |
Shipping and Storage
-85~-65℃ storage, valid for 1 year after receipt.
Avoid repeated freezing and thawing, centrifuge before opening the vial. It is recommended to aliquot for one experimental use, after aliquoting, freeze at -80℃.
Cautions
1. For your safety and health, please wear lab coat and disposable gloves.
2. This product is for scientific research purposes only.
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The product is for research purposes only and is not intended for therapeutic or diagnostic use in humans or animals. Products and content are protected by patents, trademarks, and copyrights owned by Yeasen Biotechnology. Trademark symbols indicate the country of origin, not necessarily registration in all regions.
Certain applications may require additional third-party intellectual property rights.
Yeasen is dedicated to ethical science, believing our research should address critical questions while ensuring safety and ethical standards.