描述
Interleukin-3 (IL-3) is a hematopoietic growth factor that promotes the survival, differentiation, and proliferation of directed progenitor cells of the megakaryocyte, granulocyte-macrophage, erythroid, eosinophil, basophil, and mast cell lineages.IL-3 is produced by T-cells, mast cells, and eosinophils, and enhances thrombopoietin, phagocytosis, and antibody mediated cytotoxicity. Its ability to activate monocytes suggests that IL-3 may have additional immunomodulatory roles. Much IL-3 activity is dependent on co-stimulation with other cytokines.IL-3 is a species-specific, variably glycosylated cytokine. Recombinant Human IL-3 is a 15.0 kDa globular protein containing 133 amino acid residues.
This Recombinant Human IL-3 is supplied as Lyophilized powder with high activity, high purity, low endotoxin, and NO labeling.
Product Properties
|
Synonyms |
Interleukin-3, IL-3, Hematopoietic growth factor, MCGF, Multipotential colony-stimulating factor, P-cell-stimulating factor |
|
Species |
Human |
|
Source |
CHO Cells |
|
Sequence |
Ala20-Phe152 |
|
Accession |
P08700 |
|
Tag |
NO |
|
Molecular Weight |
Predicted molecular |
|
Endotoxin |
≤10 EU/mg by the LAL method |
|
Purity |
≥95%, by SDS-PAGE (under reducing (R) & Non-reducing conditions, visualized by Coomassie staining) |
|
Activity |
Measured in a cell proliferation assay using TF-1 human erythroleukemic |
|
Formulation |
Lyophilized from a 0.22 μm-filtered solution containing PBS, 5% mannitol |
|
Appearance |
Lyophilized powder |
Shipping and Storage
-25 ~ -15 ° C storage, from the date of receipt of goods, the expiration date of 1 year. After re-solution, store at 2 ~8 °C, 7-10 days expiration date. After re-dissolution, -85 ~ -65 ° C storage, 6 months expiration date.
Compounding method
Use NO bacterial deionized water to reconstitute lyophilized proteins. It is recommended that proteins be divided for first use to avoid repeated freeze-thawing.
Cautions
1. For your safety and health, please wear lab coat and disposable gloves.
2. This product is for scientific research purposes only.
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The product is for research purposes only and is not intended for therapeutic or diagnostic use in humans or animals. Products and content are protected by patents, trademarks, and copyrights owned by Yeasen Biotechnology. Trademark symbols indicate the country of origin, not necessarily registration in all regions.
Certain applications may require additional third-party intellectual property rights.
Yeasen is dedicated to ethical science, believing our research should address critical questions while ensuring safety and ethical standards.