Beskrivelse
Interleukin 6 (IL-6) is a pleiotropic cytokine that plays an important role in host defense by regulating immune and inflammatory responses.IL-6 is produced by T cells, monocytes, fibroblasts, endothelial cells, and keratin-forming cells, and has a variety of biological functions. It stimulates B cell differentiation and antibody production, synergizes with IL-3 in megakaryocyte development and platelet production, induces the expression of hepatic acute-phase proteins, and regulates bone metabolism.IL-6 signals through the IL-6 receptor system, which consists of two chains, IL-6Rα and gp130.
This product is available as Liquid, high activity, high purity, low endotoxin, No labeling.
Product Properties
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Synonyms |
Mouse B-cell differentiation factor; B-cell stimulatory factor 2; BSF2; BSF-2; CDF; CTL differentiation factor ; HSF; hybridoma growth factor; IFNB2; IFN-beta-2; IL6; IL-6; Interferon beta-2; interleukin 6 |
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Species |
Mouse |
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Source |
HEK293 Ceslls |
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Sequence |
Phe25-Thr211 |
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Accession |
P08505 |
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Tag |
No |
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Predicted molecularmass |
21.7 KDa |
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Endotoxin |
<0.010 EU per 1 μg of the protein by the LAL method |
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Purity |
> 95%, determined by SDS-PAGE |
|
Activity |
Measured in a cell proliferation assay using T1165.85.2.1 mouse plasmacytoma cells. The ED50 for this effect is 0.02-0.06 ng/mL. |
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Formulation |
Dissolved in sterile PBS buffer. |
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Appearance |
Liquid |
Shipping and Storage
-85~-65℃ storage, valid for 1 year after receipt.
Avoid repeated freezing and thawing, centrifuge before opening the vial. It is recommended to aliquot for one experimental use, after aliquoting, freeze at -80℃.
Cautions
1. For your safety and health, please wear lab coat and disposable gloves.
2. This product is for scientific research purposes only.
Betaling og sikkerhed
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Forespørgsel
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FAQ
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