Descripción
Interleukin 19 (IL-19) is a glycosylated protein secretion that exists as a monomer.IL-19 is mainly produced by monocytes and its expression is induced by LPS, IL-4, and GM-CSF.IL-19 is expressed at a low level in B-cells.IL-19, IL-20, and IL-24 are members of the IL-20 subfamily of the IL-10 family, and they can all bind IL-20 receptors and cause activation of the STAT3 signaling pathway.IL20R2 can be paired with IL20R1 or IL22R1 to form either a type I IL20R complex or a type II IL20R complex.IL-20 and IL-24 both have signaling pathways, whereas IL-19 can only signal through the IL-20 receptor complex.
This product is available as Liquid, high purity, high activity, low endotoxin, No labeling.
Product Properties
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Synonyms |
IL-10C; IL19; IL-19; interleukin 19; MDA1; melanoma differentiation associated protein-like protein; |
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Species |
Mouse |
|
Source |
HEK293 Ceslls |
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Sequence |
Leu25-Ala176 |
|
Accession |
Q8CJ70 |
|
Tag |
No |
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Predicted molecularmass |
17.6 kDa |
|
Endotoxin |
<0.010 EU per 1 μg of the protein by the LAL method |
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Purity |
> 95%, determined by SDS-PAGE |
|
Activity |
Measured in a cell proliferation assay using BaF3 mouse pro-B cells transfected with human IL-20 R alpha and human IL-20 R beta. The EC50 for this effect is 4-20 pg/mL. |
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Formulation |
Dissolved in sterile PBS buffer. |
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Appearance |
Liquid |
Shipping and Storage
-85~-65℃ storage, valid for 1 year after receipt.
Avoid repeated freezing and thawing, centrifuge before opening the vial. It is recommended to aliquot for one experimental use, after aliquoting, freeze at -80℃.
Cautions
1. For your safety and health, please wear lab coat and disposable gloves.
2. This product is for scientific research purposes only.
Pago y seguridad
Su información de pago se procesa de forma segura. No almacenamos detalles de la tarjeta de crédito ni tenemos acceso a la información de su tarjeta de crédito.
Consulta
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Preguntas frecuentes
El producto es solo para fines de investigación y no está destinado a uso terapéutico o diagnóstico en humanos o animales. Los productos y el contenido están protegidos por patentes, marcas comerciales y derechos de autor propiedad de Yeasen Biotechnology. Los símbolos de marca comercial indican el país de origen, no necesariamente el registro en todas las regiones.
Algunas aplicaciones pueden requerir derechos de propiedad intelectual adicionales de terceros.
Yeasen se dedica a la ciencia ética y cree que nuestra investigación debe abordar cuestiones críticas al tiempo que garantiza la seguridad y los estándares éticos.