Descrição
GHR is the transmembrane receptor for growth hormone (GH) , belonging to the type I cytokine receptor family or Type 1 subfamily. It is expressed in various tissues, with higher expression in liver and skeletal muscle. Growth hormone receptor has been shown to interact with SGTA, PTPN11, Janus kinase 2, inhibitor of cytokine signaling 1, and CISH.
Specifications
|
Synonyms |
GHR,GHBP,GH receptor; |
|
Uniprot No. |
P10912-1 |
|
Source |
Recombinant Human GHR Protein is expressed from HEK293 Cells with His tag at the C-terminal. It contains Ala 27 - Tyr 264 |
|
Molecular Weight |
The protein has a predicted MW of 29.6 kDa. And it migrates as 33-43 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation. |
|
Purity |
> 95% as determined by SDS-PAGE. |
|
Endotoxin |
<1.0 EU per 1μg of the protein by the LAL method. |
|
Formulation |
Lyophilized from 0.22 μm filtered solution in PBS (pH 7.4). |
|
Reconstitution |
Centrifuge tubes before opening.The concentration of protein solution used for lyophilization is generally 1mg/mL. Dissolve lyophilized protein with sterile water to ensure the concentration is greater than 100 μg/mL. |
Storage
The product should be stored at -25~-15℃ for 1 year from the date of receipt.
2-7 days, 2 ~8 °C under sterile conditions after reconstitution.
3 months, -25~-15℃ under sterile conditions after reconstitution.
Recommend to aliquot the protein into smaller quantities when first used and avoid repeated freeze-thaw cycles.
Note
1.Please operate with lab coats and disposable gloves for your safety.
2.This product is for research use only.
Product Data
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Investigação
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