Descrição
TROP-2,also known as Tumor-Associated Calcium Signaling 2 (TACSTD2), is a type I transmembrane glycoprotein with little or no expression in adult human tissue and overexpression in various malignancies type transmembrane glycoprotein. Because it is a cell surface protein selectively expressed in tumor cells. Therefore, it may serve as a new target and may play a role in regulating the growth of cancer cells.
Specifications
|
Synonyms |
TACSTD2,GA733-1,M1S1,TROP2 |
|
Uniprot No. |
P09758-1 |
|
Source |
Recombinant Human TROP2 Protein is expressed from HEK293 Cells with His tag at the C-terminal. It contains His 27 - Thr 274. |
|
Molecular Weight |
The protein has a predicted MW of 28.96 kDa. And it migrates as 30-40 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation. |
|
Purity |
> 95% as determined by SDS-PAGE. |
|
Endotoxin |
<0.1 EU per 1μg of the protein by the LAL method. |
|
Formulation |
Lyophilized from 0.22 μm filtered solution in PBS (pH 7.4). |
|
Reconstitution |
Centrifuge tubes before opening.The concentration of protein solution used for lyophilization is generally 1mg/mL. Dissolve lyophilized protein with sterile water to ensure the concentration is greater than 100 μg/mL. |
Storage
The product should be stored at -25~-15℃ for 1 year from the date of receipt.
2-7 days, 2 ~8 °C under sterile conditions after reconstitution.
3 months, -25~-15℃ under sterile conditions after reconstitution.
Recommend to aliquot the protein into smaller quantities when first used and avoid repeated freeze-thaw cycles.
Note
1.Please operate with lab coats and disposable gloves for your safety.
2.This product is for research use only.
Product Data
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Investigação
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