描述
|
Product Name |
Cat# |
Size |
|
Recombinant Human IL-2 Protein |
90213ES10 |
10 μg |
|
90213ES50 |
50 μg |
|
|
90213ES60 |
100 μg |
|
|
90213ES80 |
1 mg |
Interleukin 2 (IL-2) is a potent immunomodulatory lymphokine produced by T cells in response to antigenic or mitogenic stimuli.IL-2/IL-2R signaling is required for T cell proliferation and other essential functions necessary for immune response.IL-2 stimulates B cell, NK cell, lymphokine-activated killer cell, monocyte, macrophage and oligodendrocyte growth and differentiation.
This product, Recombinant Human IL-2, is supplied as a lyophilized powder with high activity, high purity and low endotoxin.
Specification
|
Synonyms |
IL2, T-cell Growth Factor, TCGF, Aldesleukin |
|
Source |
E.coli-derived human IL-2 protein, Ala21-Thr153, |
|
Tag |
Not |
|
Accession |
P60568 |
|
Molecular Weight |
Approximately 15.4 kDa. |
|
AA Sequence |
APTSSSTKKT QLQLEHLLLD LQMILNGINN YKNPKLTRML TFKFYMPKKA TELKHLQCLE EELKPLEEVL NLAQSKNFHL RPRDLISNIN VIVLELKGSE TTFMCEYADE TATIVEFLNR WITFCQSIIS TLT |
|
Endotoxin |
< 1.0 EU/μg by the LAL method. |
|
Purity |
> 97% by SDS-PAGE and HPLC. |
|
Biological Activity |
Fully biologically active when compared to standard. The ED50 as determined by a cell proliferation assay using murine CTLL-2 cells is less than 0.1 ng/ml, corresponding to a specific activity of > 1.0 × 107 IU/mg. |
|
Formulation |
Lyophilized from a 0.2 μm filtered concentrated solution in 20 mM PB, pH 3.5. |
|
Physical Appearance |
White lyophilized powder |
Storage
-25 ~ -15 ° C storage, valid for 1 year after receipt.
After re-solution, store at 2 ~8 °C, 7 days expiration date. After re-dissolution, store at -85~-65°C, 3 months expiration date.
Compounding Methods
Centrifuge before uncapping to bring contents to the bottom. Reconstitute in sterile distilled water to a concentration of 0.1-1.0 mg/mL, which can be diluted even further according to subsequent experiments; dispense as a single experimental dosage and freeze at -20°C ~ -80°C to avoid repeated freezing and thawing. Do not reconstitute directly in cell culture medium.
Cautions
1. Please operate with lab coats and disposable gloves,for your safety.
2. This product is for research use only.
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