描述
Interleukin-3 (IL-3) is a hematopoietic growth factor that promotes the survival, differentiation, and proliferation of directed progenitor cells of the megakaryocyte, granulocyte-macrophage, erythroid, eosinophil, basophil, and mast cell lineages.IL-3 is produced by T-cells, mast cells, and eosinophils, and enhances thrombopoietin, phagocytosis, and antibody mediated cytotoxicity. Its ability to activate monocytes suggests that IL-3 may have additional immunomodulatory roles. Much IL-3 activity is dependent on co-stimulation with other cytokines.IL-3 is a species-specific, variably glycosylated cytokine. Recombinant Human IL-3 is a 15.0 kDa globular protein containing 133 amino acid residues.
This Recombinant Human IL-3 is supplied as Lyophilized powder with high activity, high purity, low endotoxin, and NO labeling.
Product Properties
|
Synonyms |
Interleukin-3, IL-3, Hematopoietic growth factor, MCGF, Multipotential colony-stimulating factor, P-cell-stimulating factor |
|
Species |
Human |
|
Source |
CHO Cells |
|
Sequence |
Ala20-Phe152 |
|
Accession |
P08700 |
|
Tag |
NO |
|
Molecular Weight |
Predicted molecular |
|
Endotoxin |
≤10 EU/mg by the LAL method |
|
Purity |
≥95%, by SDS-PAGE (under reducing (R) & Non-reducing conditions, visualized by Coomassie staining) |
|
Activity |
Measured in a cell proliferation assay using TF-1 human erythroleukemic |
|
Formulation |
Lyophilized from a 0.22 μm-filtered solution containing PBS, 5% mannitol |
|
Appearance |
Lyophilized powder |
Shipping and Storage
-25 ~ -15 ° C storage, from the date of receipt of goods, the expiration date of 1 year. After re-solution, store at 2 ~8 °C, 7-10 days expiration date. After re-dissolution, -85 ~ -65 ° C storage, 6 months expiration date.
Compounding method
Use NO bacterial deionized water to reconstitute lyophilized proteins. It is recommended that proteins be divided for first use to avoid repeated freeze-thawing.
Cautions
1. For your safety and health, please wear lab coat and disposable gloves.
2. This product is for scientific research purposes only.
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常問問題
本產品僅用於研究目的，不用於人類或動物的治療或診斷用途。產品和內容受以下公司的專利、商標和版權保護：
某些應用程式可能需要額外的第三方智慧財產權。