설명
The interleukin 17 (IL-17) family of proteins consists of six members (IL-17A through IL-17F) that are secreted structurally related proteins with a conserved cystine knot fold near the C-terminus but considerable sequence variation at the N-terminus.IL-17F is the ligand for IL17RA and IL17RC.The heterodimer formed by IL17A and IL17F is the ligand for the heterodimer complex formed by IL17RA and IL17RC. The heterodimer formed by IL17A and IL17F is a ligand for the heterodimeric complex formed by IL17RA and IL17RC. Involved in stimulating the production of other cytokines (e.g., IL6, IL8, and CSF2) and regulating cartilage matrix turnover.
Product Properties
|
Synonyms |
Cytokine ML-1; IL17F; IL-17F; IL24; IL-24; CANDF6; IL-17F; ML1 |
|
Species |
Human |
|
Source |
HEK293 |
|
Sequence |
Arg31-Gln163 |
|
Accession |
Q96PD4 |
|
Tag |
C-His |
|
Molecular Weight |
The protein has a predicted MW of 15.7 kDa. Due to glycosylation, the protein migrates to 23-28 kDa based on Bis-Tris PAGE result. |
|
Endotoxin |
< 1 EU/μg by the LAL method. |
|
Purity |
> 95% as determined by Bis-Tris PAGE; |
|
Activity |
ELISA Data: Immobilized Human IL-17F, His Tag at 5 μg/ml (100 μl/well) on the plate. Dose response curve for Human IL-17 R alpha, hFc Tag with the EC50 of 0.63 μg/ml determined by ELISA. |
|
Formulation |
Lyophilized from 0.22 μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
|
Appearance |
Lyophilized powder |
Shipping and Storage
-25 ~ -15 ° C storage, 1 year expiration date after receipt. After re-solution, store at 2 ~8 °C, 7 days expiration date. After re-dissolution, store at -85~-65°C, 3 months expiration date.
Compounding method
Centrifuge before opening the lid. Use distilled water to reconstitute lyophilized proteins at reconstitution concentrations greater than 100 μg/mL. it is recommended that proteins be portioned out for each experimental dosage upon first use to avoid repeated freeze-thawing.
Cautions
1. For your safety and health, please wear lab coat and disposable gloves.
2. This product is for scientific research purposes only.
결제 및 보안
귀하의 결제 정보는 안전하게 처리됩니다. 당사는 신용카드 정보를 저장하지 않으며 귀하의 신용카드 정보에 접근할 수 없습니다.
문의
당신은 또한 좋아할 수 있습니다
자주 묻는 질문
이 제품은 연구 목적으로만 사용되며 인간이나 동물의 치료 또는 진단용으로 의도되지 않았습니다. 제품과 콘텐츠는
특정 애플리케이션에는 추가적인 제3자 지적 재산권이 필요할 수 있습니다.
예슨은 윤리적 과학에 헌신하며, 우리의 연구가 안전과 윤리적 기준을 보장하는 동시에 중요한 문제를 해결해야 한다고 믿습니다.