Interleukin 12, also known as natural killer cell stimulating factor (NKSF) or cytotoxic lymphocyte maturation factor (CLMF), is a heterodimeric pleiotropic cytokine consisting of a 40 kDa (p40) subunit and a 35 kDa (p35) subunit.IL-12 is produced by macrophages and B-lymphocytes, and has been shown to have a variety of effects on T-cells and natural killer (NK) cells. IL-12 is produced by macrophages and B lymphocytes and has been shown to have multiple effects on T cells and natural killer (NK) cells. These IL-12 activities include induction of IFN-γ and TNF in resting and activated T cells and NK cells; enhancement of the cytotoxic activity of resting NK and T cells, stimulation of resting T cell proliferation in the presence of commensal progenitors; and enhancement of NK cell proliferation.IL-12 is a key mediator of cellular immunity and induces differentiation of Th1 cells from precursor T helper cells. Mouse IL-12 is active on both human and mouse cells, whereas human IL-12 is No active on murine cells.

IL-12 is a heterodimeric cytokine consisting of p35 and p40 subunits. This product is supplied as Liquid, high activity, high purity, low endotoxin, No labeling. 

Product Properties

Shipping and Storage

-85~-65℃ storage, valid for 1 year after receipt.

Avoid repeated freezing and thawing, centrifuge before opening the vial. It is recommended to aliquot for one experimental use, after aliquoting, freeze at -80℃.

Cautions

1. For your safety and health, please wear lab coat and disposable gloves.

2. This product is for scientific research purposes only.