Stem cell factor (SCF), also known as c-kit ligand (KL), mast cell growth factor (MGF), and steel factor (SLF), is a widely expressed 28 - 40 kDa type I transmembrane glycoprotein.SCF promotes the survival, differentiation, and mobilization of a wide range of cell types including myeloid, erythroid, megakaryocyte, lymphoid, germline, and melanocyte progenitors.SCF is the a major growth and activation factor for mast cells and eosinophils. Mouse SCF shares 93% amino acid sequence identity with rat SCF and 72% - 75% amino acid sequence identity with canine, feline and human SCF. Rat SCF is active in mouse and human cells, but human SCF is only weakly active in mouse cells. Non-covalent dimers of transmembrane or soluble SCF interact with the receptor tyrosine kinase SCF R/c-kit to trigger receptor dimerization and signaling.

This product is available as Liquid, high activity, high purity, low endotoxin, No labeling.

Product Properties

Shipping and Storage

-85~-65℃ storage, valid for 1 year after receipt.

Avoid repeated freezing and thawing, centrifuge before opening the vial. It is recommended to aliquot for one experimental use, after aliquoting, freeze at -80℃.

Cautions

1. For your safety and health, please wear lab coat and disposable gloves.

2. This product is for scientific research purposes only.