Beschreibung
Interleukin 7 (IL-7) is a 25 kDa cytokine in the hematopoietin family that plays an important role in lymphocyte differentiation, proliferation and survival. Mouse IL-7 shares approximately 88% aa sequence identity with rat IL-7 and 58-60% aa sequence identity with human, equine, bovine, sheep, porcine, feline and canine IL-7. Human and mouse IL-7 exhibit cross-species activity.IL-7 is produced by a variety of cells in primary and secondary lymphoid tissues, including thymus, bone marrow, and stromal epithelial cells of the intestinal tract.IL-7 contributes to the maintenance of all initial T cells and memory T cells, primarily through the promotion of the expression of the anti-apoptotic protein Bcl-2. IL-7 is essential for T cell development but not for B cell development.
This product is supplied as Liquid, high activity, high purity, low endotoxin, No labeling.
Product Properties
|
Synonyms |
Mouse IL7; mIL-7; IL-7interleukin-7; interleukin 7; Lymphopoietin-1; PBGF |
|
Species |
Mouse |
|
Source |
HEK293 Ceslls |
|
Sequence |
Glu26-Ile154 |
|
Accession |
P10168 |
|
Tag |
No |
|
Predicted molecularmass |
14.9 KDa |
|
Endotoxin |
<0.010 EU per 1 μg of the protein by the LAL method |
|
Purity |
> 95%, determined by SDS-PAGE |
|
Activity |
Measured in a cell proliferation assay using PHA-activated human peripheral blood lymphocytes (PBL). The ED50 for this effect is 0.15-0.3 ng/mL |
|
Formulation |
Dissolved in sterile PBS buffer. |
|
Appearance |
Liquid |
Shipping and Storage
-85~-65℃ storage, valid for 1 year after receipt.
Avoid repeated freezing and thawing, centrifuge before opening the vial. It is recommended to aliquot for one experimental use, after aliquoting, freeze at -80℃.
Cautions
1. For your safety and health, please wear lab coat and disposable gloves.
2. This product is for scientific research purposes only.
Zahlung und Sicherheit
Ihre Zahlungsinformationen werden sicher verarbeitet. Wir speichern weder Kreditkartendaten noch Zugriff auf Ihre Kreditkarteninformationen.
Anfrage
Sie können auch mögen
FAQ
Das Produkt ist nur für Forschungszwecke bestimmt und nicht für die therapeutische oder diagnostische Anwendung bei Menschen oder Tieren. Produkte und Inhalte sind durch Patente, Marken und Urheberrechte von
Für bestimmte Anwendungen sind möglicherweise zusätzliche geistige Eigentumsrechte Dritter erforderlich.