Beschreibung
Tumor necrosis factor alpha (TNF-α ), also known as malathin and TNFSF2, is the prototypical ligand of the TNF superfamily. It is a pleiotropic molecule that plays a central role in inflammation, immune system development, apoptosis and lipid metabolism. In ECD, mouse TNF-α shares 94% amino acid sequence identity with rat, and 70%-77% amino acid sequence identity with bovine, canine, cotton rat, equine, feline, human, porcine, rat, and rhesus monkey TNF-α is produced by a wide variety of immune cells, epithelial, endothelial, and tumor cells.
This product is supplied as Liquid, high activity, high purity, low endotoxin, No labeling.
Product Properties
|
Synonyms |
TNF; TNF, monocyte-derived; TNFA; TNF-A; TNFalpha; TNF-alpha; TNFATNF; TNFG1F; TNFSF1A; TNFSF2; tumor necrosis factor alpha; |
|
Species |
Mouse |
|
Source |
HEK293 Ceslls |
|
Sequence |
Leu80-Leu235 |
|
Accession |
P06804 |
|
Tag |
No |
|
Predicted molecularmass |
17.3 KDa |
|
Endotoxin |
<0.010 EU per 1 μg of the protein by the LAL method |
|
Purity |
> 95%, determined by SDS-PAGE |
|
Activity |
Measured in a cytotoxicity assay using L929 mouse fibroblast cells .The ED50 for this effect is 8-50 pg/mL. |
|
Formulation |
Dissolved in sterile PBS buffer. |
|
Appearance |
Liquid |
Shipping and Storage
-85~-65℃ storage, valid for 1 year after receipt.
Avoid repeated freezing and thawing, centrifuge before opening the vial. It is recommended to aliquot for one experimental use, after aliquoting, freeze at -80℃.
Cautions
1. For your safety and health, please wear lab coat and disposable gloves.
2. This product is for scientific research purposes only.
Zahlung und Sicherheit
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Anfrage
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FAQ
Das Produkt ist nur für Forschungszwecke bestimmt und nicht für die therapeutische oder diagnostische Anwendung bei Menschen oder Tieren. Produkte und Inhalte sind durch Patente, Marken und Urheberrechte von
Für bestimmte Anwendungen sind möglicherweise zusätzliche geistige Eigentumsrechte Dritter erforderlich.